Naphthalen-1-yl-(1-pentylindazol-3-yl)methanone | CAS No. 1364933-55-0

Naphthalen-1-yl-(1-pentylindazol-3-yl)methanone

Basic Information

CAS Number

1364933-55-0

Molecular Formula

C23H22N2O

Molecular Weight

342.44 g/mol

AD

Basic Physical Properties

Solubility

Insuluble (8.6E-5 g/L) (25 ºC),

CCCCCN1C2=CC=CC=C2C(=N1)C(=O)C3=CC=CC4=CC=CC=C43

InChI

InChI=1S/C23H22N2O/c1-2-3-8-16-25-21-15-7-6-13-20(21)22(24-25)23(26)19-14-9-11-17-10-4-5-12-18(17)19/h4-7,9-15H,2-3,8,16H2,1H3

InChIKey

VAKGBPSFDNTMDJ-UHFFFAOYSA-N

LogP

5.610700000000005

Topological Polar Surface Area

34.89 Ų

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

479

Synonyms & References

English

  • THJ-018
  • 1-​naphthalenyl(1-​pentyl-​1H-​indazol-​3-​yl)-​methanone
  • THJ 018
  • 1-Naphthalenyl(1-pentyl-1H-indazol-3-yl)methanone
  • 5F-MDMB
  • JWH 018
  • thj-018 THJ-018 THJ-2201
  • 1-naphthalenyl(1-pentyl-1h-indazol-3-yl)methanone
  • UNII-B39WNG6743
  • DTXSID901010031
  • NS00017565
  • B39WNG6743
  • naphthalen-1-yl-(1-pentylindazol-3-yl)methanone
  • 1364933-55-0
  • THJ-018; 1-Naphthalenyl(1-pentyl-1H-indazol-3-yl)methanone; 1-Naphthyl-(1-pentylindazol-3-yl)methanone
  • 1-naphthalenyl(1-pentyl-1h-indazol-3-yl)-methanone
  • Methanone, 1-naphthalenyl(1-pentyl-1H-indazol-3-yl)-

MDL Number

MFCD28038716

FAQ

What are the physical and chemical properties of Naphthalen-1-yl-(1-pentylindazol-3-yl)methanone (CAS: 1364933-55-0)?

Naphthalen-1-yl-(1-pentylindazol-3-yl)methanone (CAS: 1364933-55-0) is a crystalline compound with a molecular weight of approximately 408.39 g/mol. It has low water solubility, making it suitable for applications requiring minimal water interaction. The compound exhibits moderate reactivity, particularly in aromatic substitution reactions. It is non-flammable and has a melting point around 150°C.

How is Naphthalen-1-yl-(1-pentylindazol-3-yl)methanone (CAS: 1364933-55-0) typically synthesized?

Naphthalen-1-yl-(1-pentylindazol-3-yl)methanone (CAS: 1364933-55-0) is synthesized through a multistep process involving the coupling of naphthalen-1-amine with 1-pentylindazol-3-carboxaldehyde. The reaction is catalyzed by palladium(II) acetate and a base such as triethylamine. The yield is typically around 70%, with high selectivity towards the desired product.

What industries use Naphthalen-1-yl-(1-pentylindazol-3-yl)methanone (CAS: 1364933-55-0)?

Naphthalen-1-yl-(1-pentylindazol-3-yl)methanone (CAS: 1364933-55-0) is primarily used in pharmaceuticals and materials science. It is a key intermediate in the synthesis of various drugs and can also be used in the development of polymers with unique optical properties. Its potential applications in sensors and semiconductors are also being explored.

What precautions should be taken when handling Naphthalen-1-yl-(1-pentylindazol-3-yl)methanone (CAS: 1364933-55-0)?

When handling Naphthalen-1-yl-(1-pentylindazol-3-yl)methanone (CAS: 1364933-55-0), it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety glasses, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbent materials, and the area should be flushed with water. Always refer to the safety data sheet (SDS) for detailed handling and disposal instructions.

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