Minocycline hydrochloride

Basic Information

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CAS Number

13614-98-7

Molecular Formula

C23H28ClN3O7

Molecular Weight

493.9 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

213-218°C

Boiling Point

813℃

Density

1.0170

Water Solubility

Freely soluble in water

Flash Point

>110°(230°F)

Specific Rotation

-170 ~ -180° (c=0.5, 0.1ml/L HCl)

SMILES

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CN(C)C1C2CC3CC4=C(C=CC(=C4C(=C3C(=O)C2(C(=C(C1=O)C(=O)N)O)O)O)O)N(C)C.Cl

InChI

InChI=1S/C23H27N3O7.ClH/c1-25(2)12-5-6-13(27)15-10(12)7-9-8-11-17(26(3)4)19(29)16(22(24)32)21(31)23(11,33)20(30)14(9)18(15)28;/h5-6,9,11,17,27-28,31,33H,7-8H2,1-4H3,(H2,24,32);1H/t9-,11-,17-,23-;/m0./s1

InChIKey

WTJXVDPDEQKTCV-VQAITOIOSA-N

LogP

0.45180000000000037

Topological Polar Surface Area

164.63 Å²

Hydrogen Bond Donor/Acceptor

6 / 10

Complexity

971

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1(b) Class 6.1(b)

Stability

Light Sensitive

Sensitiveness

thermally sensitive

Synonyms & References

English

BCP06597
NCGC00096006-01
Minocycline (hydrochloride)
Minocin
(4S,4aS,5aR,12aR)-4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;hydrochloride
Minocyclinhydrochlorid
13614-98-7
Minomycin
Minocycline hydrochloride, crystalline
SMR001906766
MFCD00083669
[4S-(4alpha,4aalpha,5aalpha,12aalpha)]-4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxonaphthacene-2-carboxamide monohydrochloride
MINOCYCLINE HYDROCHLORIDE [USP MONOGRAPH]
NSC-757120
Tox21_111250_1
Periocline
Minocycline HCl
MINOCYCLINE HYDROCHLORIDE
Minocycline hydrochloride (internal use)
NSC-141993
CHEBI:50697
Minocycline Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material
NCGC00178854-03
Minocycline hydrochloride (JP17/USP)
HMS1568P12
CHEMBL4576719
MINOCYCLINE HYDROCHLORIDE [MI]
Arestin
Minocycline (as hydrochloride)
s4226
GLMUAFMGXXHGLU-VQAITOIOSA-N

MDL Number

MFCD00083669

Customs Code

2942000000

FAQ

What is Minocycline hydrochloride (CAS: 13614-98-7)?

Minocycline hydrochloride is an antibiotic compound with the chemical formula C19H23ClN2O4. It is a semi-synthetic tetracycline derivative known for its broad-spectrum antibacterial activity. This compound is commonly used in pharmaceutical preparations and is characterized by its ability to inhibit bacterial protein synthesis by binding to the 30S ribosomal subunit.

What are the main uses of Minocycline hydrochloride (CAS: 13614-98-7)?

Minocycline hydrochloride is primarily used in the treatment of bacterial infections such as acne, respiratory tract infections, and urinary tract infections. It is also applied in veterinary medicine and research for its antimicrobial properties. Its use extends to areas requiring broad-spectrum antibiotics, including dermatology and infectious disease management.

Is Minocycline hydrochloride (CAS: 13614-98-7) safe?

Minocycline hydrochloride is generally considered safe when used as directed, but it may cause side effects such as gastrointestinal discomfort or photosensitivity. Proper handling and adherence to safety guidelines are essential. It is classified as a prescription medication and should be used under medical supervision to ensure appropriate dosing and minimize risks.

How should Minocycline hydrochloride (CAS: 13614-98-7) be stored?

Minocycline hydrochloride should be stored in a cool, dry place away from direct light. It is typically kept in airtight containers to maintain its stability and potency. The recommended storage temperature is between 15°C to 25°C, and it should be protected from moisture and humidity to prevent degradation.