6-[(4-Methylphenyl)sulfonyl]-2-oxa-6-azaspiro[3.3]heptane

Basic Information

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CAS Number

13573-28-9

Molecular Formula

C12H15NO3S

Molecular Weight

253.32 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Boiling Point

411°C at 760 mmHg

SMILES

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CC1=CC=C(C=C1)S(=O)(=O)N2CC3(C2)COC3

InChI

InChI=1S/C12H15NO3S/c1-10-2-4-11(5-3-10)17(14,15)13-6-12(7-13)8-16-9-12/h2-5H,6-9H2,1H3

InChIKey

DVSLPPSXVDZQHH-UHFFFAOYSA-N

LogP

1.01592

Topological Polar Surface Area

46.61 Å²

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

381

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

6-(4-Methylbenzene-1-sulfonyl)-2-oxa-6-azaspiro[3.3]heptane
BCP19820
6-Tosyl-2-oxa-6-azaspiro[3.3]heptane 95+%
W-205474
6-(4-methylphenyl)sulfonyl-2-oxa-6-azaspiro[3.3]heptane
CS-B0206
6-TOSYL-2-OXA-6-AZASPIRO[3.3]HEPTANE
6-(p-toluenesulfonyl)-2-oxa-6-azaspiro[3.3]heptane
MFCD13180735
2-OXA-6-AZASPIRO[3.3]HEPTANE, 6-[(4-METHYLPHENYL)SULFONYL]-
6-(Toluene-4-sulfonyl)-2-oxa-6-azaspiro[3.3]heptane
13573-28-9
FT-0686081
A846382
DVSLPPSXVDZQHH-UHFFFAOYSA-N
DS-8943
6-(4-methylbenzenesulfonyl)-2-oxa-6-azaspiro[3.3]heptane
6-(p-toluenesulfonyl)-2-o...
6-(TOLUENE-4-SULFONYL)-2-OXA-6-AZA-SPIRO[3.3]HEPTANE
SY096958
SCHEMBL896463
AKOS015950453
DTXSID90632854
6-toluene-4-sulfonyl-2-oxa-6-azaspiro[3.3]heptane
AM20020016
PB16544
2-Oxa-6-azaspiro[3.3]heptane, 6-[(4-methylphenyl)sulfonyl]-
6-Tosyl-2-oxa-6-azaspiro[3.3]heptane
6-(p-Toluenesulfonyl)-2-oxa-6-azaspiro[3.3]heptane
6-(toluene-4-sulfonyl)-2-oxa-6-aza-spiro[3.3]heptane
6-[(4-methylphenyl)sulfonyl]-2-oxa-6-azaspiro[3.3]heptane

MDL Number

MFCD13180735

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 6-[(4-Methylphenyl)sulfonyl]-2-oxa-6-azaspiro[3.3]heptane (CAS: 13573-28-9)?

6-[(4-Methylphenyl)sulfonyl]-2-oxa-6-azaspiro[3.3]heptane has a crystalline form and a molecular weight of approximately 318.34 g/mol. It is slightly soluble in common organic solvents but not in water. This compound is known for its stability and moderate reactivity, particularly in acidic conditions.

How is 6-[(4-Methylphenyl)sulfonyl]-2-oxa-6-azaspiro[3.3]heptane (CAS: 13573-28-9) typically synthesized?

6-[(4-Methylphenyl)sulfonyl]-2-oxa-6-azaspiro[3.3]heptane can be synthesized through a multistep process involving the formation of a sulfonyl chloride, followed by an azaspiro[3.3]heptane ring closure. The synthesis typically uses mild conditions and may involve the use of a catalyst to enhance selectivity and yield.

What industries use 6-[(4-Methylphenyl)sulfonyl]-2-oxa-6-azaspiro[3.3]heptane (CAS: 13573-28-9)?

6-[(4-Methylphenyl)sulfonyl]-2-oxa-6-azaspiro[3.3]heptane is primarily used in pharmaceutical applications due to its chemical structure and potential biological activities. It may also find use in the polymer industry for modifying polymer properties and in analytical chemistry for sensor applications.

What precautions should be taken when handling 6-[(4-Methylphenyl)sulfonyl]-2-oxa-6-azaspiro[3.3]heptane (CAS: 13573-28-9)?

When handling 6-[(4-Methylphenyl)sulfonyl]-2-oxa-6-azaspiro[3.3]heptane, ensure the use of appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or fume hood to minimize exposure. Spills should be cleaned up using appropriate chemical spill kits. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.