2-Methyl-2-propanyl (4-piperidinylmethyl)carbamate

Basic Information

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CAS Number

135632-53-0

Molecular Formula

C11H22N2O2

Molecular Weight

214.31 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

107.0 to 111.0 deg-C

Boiling Point

321.8℃ at 760 mmHg

Flash Point

148.4℃

Solubility

Soluble in DMSO.

SMILES

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CC(C)(C)OC(=O)NCC1CCNCC1

InChI

InChI=1S/C11H22N2O2/c1-11(2,3)15-10(14)13-8-9-4-6-12-7-5-9/h9,12H,4-8H2,1-3H3,(H,13,14)

InChIKey

VHYXAWLOJGIJPC-UHFFFAOYSA-N

LogP

1.5107

Topological Polar Surface Area

50.36 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

205

Safety Information

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GHS Hazard Pictograms

H314

H318

Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

Hazard Class

Class 8 Class 8

Synonyms & References

English

4-(N-tert-butyloxycarbonylaminomethyl) piperidine
1,1-dimethylethyl (4piperidinylmethyl)-carbamate
[piperidin-4-ylmethyl]-carbamic acid t-butyl ester
DTXSID00352339
(Boc-4-Aminomethyl)Piperidine
4-tert-Butoxycarbonylaminomethylpiperidine
tert-butyl N-(piperidin-4-ylmethyl)carbamate
Tert-butyl piperidine-4-ylmethyl-carbamate
F8880-5628
tert-butyl N-[(piperidin-4-yl)methyl]carbamate
tert-butyl n-(4-piperidinylmethyl)carbamate
(4-Piperidylmethyl)carbamic Acid tert-Butyl Ester
1,1-dimethylethyl (4-piperidinylmethyl)carbamate
4-N-Boc-aminomethyl piperidine
piperidin-4-ylmethyl-carbamic acid t-butyl ester
4-(aminomethyl)piperidine, 4-boc protected
tert-butyl piperidin-4-ylmethylcarbamate
4-(boc-aminomethyl)-piperidine
CS-W009217
4-(N-tert-butyloxycarbonylaminomethyl)piperidine
B56683
tert-butyl piperidin-4-ylmethyl-carbamate
4-tert-butyloxycarbonylaminomethylpiperidine
4-(tert.-Butyloxycarbonyl)aminomethyl-piperidine
tert-butyl (piperidin-4-ylmethyl)carbamate
PIP(4-BOC-AM)
4-(tert-Butoxycarbonylaminomethyl)piperidine, AldrichCPR
AC-134
4-(t-butyloxycarbonyl-aminomethyl)-piperidine
B4444
BP-11259

MDL Number

MFCD01631214

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2-Methyl-2-propanyl (4-piperidinylmethyl)carbamate (CAS: 135632-53-0)?

2-Methyl-2-propanyl (4-piperidinylmethyl)carbamate has a crystalline form with a molecular weight of approximately 232.33 g/mol. It is slightly soluble in water and more soluble in organic solvents such as ethanol and acetone. This compound is reactive towards nucleophiles, making it useful in various chemical reactions. Its physical properties include a melting point of around 60-62°C and a boiling point of approximately 220°C at 10 mmHg pressure.

How is 2-Methyl-2-propanyl (4-piperidinylmethyl)carbamate (CAS: 135632-53-0) typically synthesized?

2-Methyl-2-propanyl (4-piperidinylmethyl)carbamate is typically synthesized via a reaction between 2-methyl-2-propanol and 4-piperidinylmethyl isocyanate. The reaction is performed in the presence of a base, such as triethylamine, to enhance the nucleophilicity of the isocyanate. The process yields a high purity compound with good selectivity and a high yield of up to 90%.

What industries use 2-Methyl-2-propanyl (4-piperidinylmethyl)carbamate (CAS: 135632-53-0)?

2-Methyl-2-propanyl (4-piperidinylmethyl)carbamate finds applications in various industries. It is used in the pharmaceutical industry for the synthesis of certain drugs, in polymer chemistry for functionalization of polymers, and in the production of sensors and semiconductors. Its reactivity and specific chemical properties make it suitable for these applications.

What precautions should be taken when handling 2-Methyl-2-propanyl (4-piperidinylmethyl)carbamate (CAS: 135632-53-0)?

When handling 2-Methyl-2-propanyl (4-piperidinylmethyl)carbamate, it is important to wear appropriate personal protective equipment (PPE) including gloves, lab coat, and safety goggles. The compound should be used in a well-ventilated area or under a fume hood. Spills should be cleaned up using an appropriate absorbent material and disposed of according to local regulations. Always refer to the safety data sheet (SDS) for detailed handling and storage instructions.