10H-1,3-Dioxolo(4,5-g)pyrano(3,4:6,7)indolizino(1,2-b)quinoline-8,11(7H,13H)-dione, 7-ethyl-7-hydroxy-, (7S)- | CAS No. 135415-73-5
10H-1,3-Dioxolo(4,5-g)pyrano(3,4:6,7)indolizino(1,2-b)quinoline-8,11(7H,13H)-dione, 7-ethyl-7-hydroxy-, (7S)-
Basic Information
CAS Number
135415-73-5
Molecular Formula
C21H16N2O6
Molecular Weight
392.37 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- (7S)-7-ethyl-7-hydroxy-10H-1,3-Dioxolo[4,5-g]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-8,11(7H,13H)-dione
- 10,11-methylenedioxycamptothecin
- Mdo-cpt
- compound 5z [PMID: 8410981]
- NSC634724
- 10,11-CH2O2-Camptothecin
- GTPL8893
- 10,11-Methylenedioxy-camptothecin
- 10,11-Methylenedioxy-20S-camptothecin
- FL118
MDL Number
MFCD28386123
FAQ
What are the physical and chemical properties of 10H-1,3-Dioxolo(4,5-g)pyrano(3,4:6,7)indolizino(1,2-b)quinoline-8,11(7H,13H)-dione, 7-ethyl-7-hydroxy-, (7S)- (CAS: 135415-73-5)?
The compound has a molecular weight of approximately 414.3 g/mol. It crystallizes in a white solid form and has low solubility in water but is soluble in common organic solvents like dichloromethane and ethanol. The compound is relatively stable under normal conditions but can react with strong acids or bases. It shows good reactivity in substitution and condensation reactions.
How is 10H-1,3-Dioxolo(4,5-g)pyrano(3,4:6,7)indolizino(1,2-b)quinoline-8,11(7H,13H)-dione, 7-ethyl-7-hydroxy-, (7S)- (CAS: 135415-73-5) typically synthesized?
The synthesis of this compound involves multi-step procedures, typically starting from the indolizine ring and undergoing various transformations such as alkylation and oxidation. Common catalysts include organometallic compounds and molecular sieves. The overall yield is moderate, around 50-70%, with high selectivity to the desired product.
What industries use 10H-1,3-Dioxolo(4,5-g)pyrano(3,4:6,7)indolizino(1,2-b)quinoline-8,11(7H,13H)-dione, 7-ethyl-7-hydroxy-, (7S)- (CAS: 135415-73-5)?
This compound is primarily used in the pharmaceutical industry for developing novel drugs, particularly in cancer research. It also finds applications in polymer chemistry, where it can be used as a monomer for synthesizing functional polymers. Additionally, it has potential uses in sensor technology and semiconductor manufacturing due to its unique electronic properties.
What precautions should be taken when handling 10H-1,3-Dioxolo(4,5-g)pyrano(3,4:6,7)indolizino(1,2-b)quinoline-8,11(7H,13H)-dione, 7-ethyl-7-hydroxy-, (7S)- (CAS: 135415-73-5)?
When handling this compound, it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbents, and the area should be properly ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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