Methyl {4,6-diamino-2-[5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl}carbamate | CAS No. 1350653-20-1

Methyl {4,6-diamino-2-[5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl}carbamate

Basic Information

CAS Number

1350653-20-1

Molecular Formula

C19H16F2N8O2

Molecular Weight

426.39 g/mol

AD

Basic Physical Properties

COC(=O)Nc1c(N)nc(nc1N)c1nn(c2c1cc(F)cn2)Cc1ccccc1F

InChI

InChI=1S/C19H16F2N8O2/c1-31-19(30)25-14-15(22)26-17(27-16(14)23)13-11-6-10(20)7-24-18(11)29(28-13)8-9-4-2-3-5-12(9)21/h2-7H,8H2,1H3,(H,25,30)(H4,22,23,26,27)

InChIKey

QZFHIXARHDBPBY-UHFFFAOYSA-N

LogP

2.5575

Topological Polar Surface Area

146.86 Ų

Hydrogen Bond Donor/Acceptor

5 / 10

Complexity

622

Synonyms & References

English

  • Methyl (4,6-diamino-2-(5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)carbamate
  • methyl N-[4,6-diamino-2-[5-fluoro-1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl]carbamate
  • Vericiguat
  • BAY1021189
  • BAY 1021189
  • LV66ADM269
  • Methyl (4,6-diamino-2-(5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo(3,4-b)pyridin-3-yl)pyrimidin-5-yl)carbamate
  • Methyl {4,6-diamino-2-[5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-
  • methyl (4,6-diamino-2-(5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)carbamate

MDL Number

MFCD28502029

FAQ

What regulatory guidelines apply to Methyl {4,6-diamino-2-[5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl}carbamate (CAS: 1350653-20-1)?

This compound falls under various regulatory guidelines including GHS for hazardous classification, REACH for European Union regulations, and FDA and EPA requirements for safety and environmental impact. Manufacturers and distributors must ensure compliance with these regulations for labeling, transportation, and disposal.

Are there alternatives to Methyl {4,6-diamino-2-[5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl}carbamate (CAS: 1350653-20-1) in synthesis?

Alternative reagents include other carbamates or analogs such as related pyrimidinyl derivatives. Isomers and analogs can be used depending on the specific synthesis requirements, but it is important to evaluate their reactivity and properties.

What is the market or research trend for Methyl {4,6-diamino-2-[5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl}carbamate (CAS: 1350653-20-1)?

The market trend for this compound is driven by ongoing research in medicinal chemistry and drug development. There is a growing interest in its potential applications in treating diseases such as cancer and inflammation. Research is also focusing on its synthesis and optimization for pharmaceutical purposes.

How should waste containing Methyl {4,6-diamino-2-[5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl}carbamate (CAS: 1350653-20-1) be handled?

Waste containing this compound should be collected in appropriate containers and handled according to local regulations. Incineration or professional waste disposal services are recommended. Ensure that all precautions for environmental protection are followed to prevent contamination of water and soil.

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