(3-exo)-8-Methyl-8-azabicyclo[3.2.1]octan-3-ol

Basic Information

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CAS Number

135-97-7

Molecular Formula

C8H15NO

Molecular Weight

141.21 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

Powder

Melting Point

107-112°C

Boiling Point

241°C at 760 mmHg

Flash Point

112.5 °C

Refractive Index

1.4811 (estimate)

SMILES

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CN1C2CCC1CC(C2)O

InChI

InChI=1S/C8H15NO/c1-9-6-2-3-7(9)5-8(10)4-6/h6-8,10H,2-5H2,1H3/t6-,7+,8-

InChIKey

CYHOMWAPJJPNMW-RNLVFQAGSA-N

LogP

0.6039000000000001

pKa

3.80(at 15℃)

Topological Polar Surface Area

23.47 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

123

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

rel-(1R,3s,5S)-8-Methyl-8-azabicyclo[3.2.1]octan-3-ol
CAS-120-29-6
3beta-Tropanol
(1R,3r,5S)-8-Methyl-8-azabicyclo[3.2.1]oct-3-ol (Tropine)
Tropine, >=97.0% (NT)
120-29-6
A-804485
tropan-3alpha-ol
endo-8-methyl-8-azabicyclo[3.2.1]octan-3-ol
DTXCID9029358
exo-8-Methyl-8-azabicyclo(3.2.1)octan-3-ol
2,3-Dihydro-3alpha-hydroxytropidine
ENDO-8-METHYL-8-AZABICYCLO(3.2.1)OCTAN-3-OL
NS00073198
Tropine
NSC 43871
Pseudotropine
8-Azabicyclo(3.2.1)octan-3-ol, 8-methyl-, exo-
HMS3886K07
5-21-01-00219 (Beilstein Handbook Reference)
PSEUDOTROPINE [MI]
NCGC00016370-01
1alphaH,5alphaH-Tropan-3beta-ol
TROPINE [MI]
CS-0078616
TROPINE [EP IMPURITY]
7YXR19M72Y
Tropisetron Hydrochloride Imp. A (EP); Tropisetron Imp. A (EP); (1R,3r,5S)-8-Methyl-8-azabicyclo[3.2.1]oct-3-ol; Tropine; Tropisetron Hydrochloride Impurity A; Tropisetron Impurity A
NS00015118
1alphaH,5alphaH-Tropan-3alpha-ol
135-97-7

MDL Number

MFCD00078060

FAQ

What is (3-exo)-8-Methyl-8-azabicyclo[3.2.1]octan-3-ol (CAS: 135-97-7)?

(3-exo)-8-Methyl-8-azabicyclo[3.2.1]octan-3-ol, with the CAS number 135-97-7, is a cyclic tertiary amine compound. It contains an eight-membered ring with one nitrogen atom and a methyl group at the 8-position, along with an alcohol functional group at the 3-position. This compound is known for its unique structural features and is often used in various chemical applications due to its reactivity and stability in specific conditions.

What are the main uses of (3-exo)-8-Methyl-8-azabicyclo[3.2.1]octan-3-ol (CAS: 135-97-7)?

(3-exo)-8-Methyl-8-azabicyclo[3.2.1]octan-3-ol (CAS: 135-97-7) is primarily used in pharmaceutical research as a building block for drug development. It also finds applications in organic synthesis, particularly in the creation of complex molecules. Its utility in research and industry is due to its ability to participate in various chemical reactions and its structural versatility.

Is (3-exo)-8-Methyl-8-azabicyclo[3.2.1]octan-3-ol (CAS: 135-97-7) safe?

The safety of (3-exo)-8-Methyl-8-azabicyclo[3.2.1]octan-3-ol (CAS: 135-97-7) depends on the handling conditions. While it is generally considered stable under normal laboratory conditions, it should be handled with care to avoid direct contact with skin or inhalation. Protective gloves, goggles, and a well-ventilated workspace are recommended. Safety data sheets (SDS) should be consulted for detailed guidelines.

How should (3-exo)-8-Methyl-8-azabicyclo[3.2.1]octan-3-ol (CAS: 135-97-7) be stored?

(3-exo)-8-Methyl-8-azabicyclo[3.2.1]octan-3-ol (CAS: 135-97-7) should be stored in a cool, dry, and dark place, ideally at 2-8°C. It is recommended to keep it in a sealed container to prevent moisture ingress and maintain its stability. Avoid exposure to air and light to preserve its chemical integrity over time.