2-Deoxy-2,2-difluoro-3,5-dibenzoate-1-methanesulfonate β-D-erythro-Pentofuranose | CAS No. 134877-43-3

2-Deoxy-2,2-difluoro-3,5-dibenzoate-1-methanesulfonate β-D-erythro-Pentofuranose

Basic Information

CAS Number

134877-43-3

Molecular Formula

C20H18F2O8S

Molecular Weight

456.42 g/mol

AD

Basic Physical Properties

CS(=O)(=O)OC1C(C(C(O1)COC(=O)C2=CC=CC=C2)OC(=O)C3=CC=CC=C3)(F)F

InChI

InChI=1S/C20H18F2O8S/c1-31(25,26)30-19-20(21,22)16(29-18(24)14-10-6-3-7-11-14)15(28-19)12-27-17(23)13-8-4-2-5-9-13/h2-11,15-16,19H,12H2,1H3/t15-,16-,19+/m1/s1

InChIKey

LIAQHZDWFACWFK-MDZRGWNJSA-N

LogP

2.4054

Topological Polar Surface Area

105.20000000000002 Ų

Hydrogen Bond Donor/Acceptor

0 / 8

Complexity

739

Synonyms & References

English

  • 2-Deoxy-2,2-difluoro-3,5-O-dibenzoylribose mesylate
  • 3,5-Bis(benzoyl)-1-methanesulfonyloxy-2-deoxy-2,2-difluororibose(beta-form)
  • AKOS015896201
  • ((2R3R5R)-3-(Benzoyloxy)-44-difluoro-5-((methylsulfonyl)oxy)tetrahydrofuran-2-yl)methyl benzoate
  • D84356
  • ((2R,3R,5R)-3-(Benzoyloxy)-4,4-difluoro-5-((methylsulfonyl)oxy)tetrahydrofuran-2-yl)methyl benzoate
  • 3,5-bis(benzoyl)-1-methanesulfonyloxy-2-deoxy-2,2-difluororibose
  • SCHEMBL8713071
  • MFCD22422479
  • LIAQHZDWFACWFK-GPMSIDNRSA-N
  • alpha-D-erythro-Pentofuranose, 2-deoxy-2,2-difluoro-, 3,5-dibenzoate 1-methanesulfonate
  • [(2R,3R,5R)-3-benzoyloxy-4,4-difluoro-5-methylsulfonyloxyoxolan-2-yl]methyl benzoate
  • 134877-43-3
  • CS-0357062
  • ((2R,3R,5R)-3-(Benzoyloxy)-4,4-difluoro-5-((methylsulfonyl)oxy)tetrahydrofuran-2-yl)methylbenzoate
  • [(2R,3R,5R)-3-(BENZOYLOXY)-4,4-DIFLUORO-5-(METHANESULFONYLOXY)OXOLAN-2-YL]METHYL BENZOATE
  • DTXSID301129773
  • ((2R,3R,5R)-3-(Benzoyloxy)-4,4-difluoro-5-((methyl-sulfonyl)oxy)tetrahydrofuran-2-yl)methyl benzoate
  • DS-16124
  • C20H18F2O8S
  • 134877-42-2
  • 3,5-Di-O-benzoyl-2-deoxy-2,2-difluoro-1-O- methanesulfonyl-D-ribofuranose
  • 3,5-Bis(benzoyl)-1-methanesulfonyloxy-2-deoxy-2,2-difluororibose
  • ((2R,3R,5S)-3-(Benzoyloxy)-4,4-difluoro-5-((methylsulfonyl)oxy)tetrahydrofuran-2-yl)methyl benzoate
  • 3,5-Di-O-benzoyl-2-deoxy-2,2-difluoro-1-O-methanesulfonyl-D-ribofuranoside
  • (3S,4R)-3-Benzoyl-2,2-difluoro-3,4,5-trihydroxy-6-oxo-6-phenylhexanoic Methanesulfonic anhydride
  • 1-methylsulfonyl-2-deoxy-2,2-difluoro-D-ribofu
  • 2-deoxy-2,2-difluoro-D-ribofuranose-3,4-dibenzoate-1-methanesulfonate
  • 2-deoxy-D-erythro-2,2-difluororibofuranose 3,5-dibenzoate 1-methanesulfonate
  • 3,5-di-O-benzoyl-2-deoxy-2,2-difluoro-1-O-methanesulfonyl-D-erythro-pentofuranose
  • 3,5-di-O-benzoyl-2-deoxy-2,2-difluoro-D-ribofuranosyl mesylate

MDL Number

MFCD09842850

FAQ

What are the physical and chemical properties of 2-Deoxy-2,2-difluoro-3,5-dibenzoate-1-methanesulfonate β-D-erythro-Pentofuranose (CAS: 134877-43-3)?

2-Deoxy-2,2-difluoro-3,5-dibenzoate-1-methanesulfonate β-D-erythro-Pentofuranose (CAS: 134877-43-3) is a solid with a crystalline form. Its molecular weight is approximately 548.5 g/mol. It has a low solubility in water but is more soluble in organic solvents. This compound is known for its limited reactivity, primarily due to its stable structure.

How is 2-Deoxy-2,2-difluoro-3,5-dibenzoate-1-methanesulfonate β-D-erythro-Pentofuranose (CAS: 134877-43-3) typically synthesized?

2-Deoxy-2,2-difluoro-3,5-dibenzoate-1-methanesulfonate β-D-erythro-Pentofuranose (CAS: 134877-43-3) is synthesized through a multi-step process involving the protection of the hydroxyl group, followed by the introduction of the difluorobenzene and benzoate moieties. The reaction typically involves the use of catalysts such as sulfuric acid, leading to good yield and selectivity.

What industries use 2-Deoxy-2,2-difluoro-3,5-dibenzoate-1-methanesulfonate β-D-erythro-Pentofuranose (CAS: 134877-43-3)?

2-Deoxy-2,2-difluoro-3,5-dibenzoate-1-methanesulfonate β-D-erythro-Pentofuranose (CAS: 134877-43-3) is primarily used in pharmaceuticals and academic research due to its unique structural characteristics. It may also find applications in the development of novel biomedical compounds and materials.

What precautions should be taken when handling 2-Deoxy-2,2-difluoro-3,5-dibenzoate-1-methanesulfonate β-D-erythro-Pentofuranose (CAS: 134877-43-3)?

When handling 2-Deoxy-2,2-difluoro-3,5-dibenzoate-1-methanesulfonate β-D-erythro-Pentofuranose (CAS: 134877-43-3), ensure proper personal protective equipment (PPE) such as gloves and goggles. Work in a well-ventilated area or fume hood to minimize inhalation risks. In case of a spill, immediately evacuate the area and contact the appropriate environmental health and safety personnel for cleanup. Always consult the Material Safety Data Sheet (MSDS) for detailed safety information.

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