4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone | CAS No. 134678-17-4

4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone

Basic Information

CAS Number

134678-17-4

Molecular Formula

C8H11N3O3S

Molecular Weight

229.26 g/mol

AD

Basic Physical Properties

Physical State

Powder

Melting Point

175.0 to 179.0 deg-C

Boiling Point

475.4°C at 760 mmHg

Density

1.7±0.1 g/cm3

Flash Point

9℃

Solubility

water: soluble10mg/mL, clear

Refractive Index

-142 ° (C=1, MeOH)

Vapor Pressure

0.0±2.7 mmHg at 25°C

Specific Rotation

-148° - -137° (c=1,MeOH)

C1C(OC(S1)CO)N2C=CC(=NC2=O)N

InChI

InChI=1S/C8H11N3O3S/c9-5-1-2-11(8(13)10-5)6-4-15-7(3-12)14-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7+/m0/s1

InChIKey

JTEGQNOMFQHVDC-NKWVEPMBSA-N

LogP

-0.5941000000000001

Topological Polar Surface Area

90.36999999999999 Ų

Hydrogen Bond Donor/Acceptor

3 / 6

Complexity

331

Safety Information

View Safety Information

GHS Hazard Pictograms

H373H373

Hazard Statement

H373 Causes damage to organs through prolonged or repeated exposure
Specific target organ toxicity, repeated exposure

Synonyms & References

English

  • NSC-760061
  • C07065
  • P17147
  • TRIZIVIR COMPONENT LAMIVUDINE
  • Z1509637175
  • LAMIVUDINE TEVA PHARMA B.V.
  • 4-AMINO-1-((2R,5S)-2-(HYDROXYMETHYL)-1,3-OXATHIOLAN-5-YL)PYRIMIDIN-2(1H)-ONE [WHO-IP]
  • Epivir(TM)
  • (-)-(2'R,5'S)-1-[2'-Hydroxymethyl-5'-(1,3-oxathiolanyl)]cytosine
  • HY-B0250
  • TELURA COMPONENT OF LAMIVUDINE
  • LAMIVUDINE [JAN]
  • LAMIVUDINE COMPONENT OF COMBIVIR
  • LAMIVUDINE [WHO-IP]
  • Lamivudine, British Pharmacopoeia (BP) Reference Standard
  • Heptodin
  • LAMIVUDINE [USP-RS]
  • Hepitec
  • JTEGQNOMFQHVDC-NKWVEPMBSA-N
  • LAMIVUDINE COMPONENT OF LAMIVUDINE/ZIDOVUDINE TEVA
  • 134678-17-4
  • NCGC00159341-18
  • Lamivir
  • SCHEMBL109675
  • 1117764-41-6
  • NSC 760061
  • LAMIVUDINE [MART.]
  • MFCD00870542
  • GR-109714X
  • 3'-Thia-2',3'-dideoxycytidine
  • BCH 189, (-)-

MDL Number

MFCD00869739

Customs Code

2934999090

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