3-bromopyridin-2-ol

Basic Information

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CAS Number

13466-43-8

Molecular Formula

C5H4BrNO

Molecular Weight

174 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

178.0 to 186.0 deg-C

Water Solubility

Slightly soluble in water.

Flash Point

157.4℃

SMILES

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C1=CNC(=O)C(=C1)Br

InChI

InChI=1S/C5H4BrNO/c6-4-2-1-3-7-5(4)8/h1-3H,(H,7,8)

InChIKey

YDUGVOUXNSWQSW-UHFFFAOYSA-N

LogP

1.5496999999999999

Topological Polar Surface Area

33.120000000000005 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

171

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

3-Bromo-2-hydroxypyridine
B2330
SCHEMBL118163
3-bromo-1H-2-pyridone
FS-2164
3-Bromo-2-pyridone
3-bromo-1H-pyridin-2-one
bromopyridone
2(1H)-Pyridinone, 3-bromo-
DTXSID30355959
SY008491
3-bromopyridone
3-bromopyridin-2-ol;3-BROMOPYRIDIN-2(1H)-ONE
InChI=1/C5H4BrNO/c6-4-2-1-3-7-5(4)8/h1-3H,(H,7,8)
PB12284
3-Bromo-2-hydroxy-pyridine
3-bromo-2(1H)-pyridinone
3-Bromo-pyridin-2-ol
HY-W003045
AKOS022381261
AKOS000320198
monobromopyridone
AM20050778
3-BROMOPYRIDIN-2(1H)-ONE
bromohydroxypyridine
3-Bromo-2-pyridinol
YDUGVOUXNSWQSW-UHFFFAOYSA-N
3-Bromo-2-hydroxypyridine, 97%
CS-W003045
FT-0645792
F1371-0174

MDL Number

MFCD03411569

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 3-bromopyridin-2-ol (CAS: 13466-43-8)?

3-Bromopyridin-2-ol (CAS: 13466-43-8) is a crystalline solid with a molecular weight of approximately 179.01 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetone. Chemically, it is reactive and can undergo nucleophilic substitution reactions, making it useful in organic synthesis.

How is 3-bromopyridin-2-ol (CAS: 13466-43-8) typically synthesized?

3-Bromopyridin-2-ol (CAS: 13466-43-8) can be synthesized via bromination of 2-pyridol using NBS (N-bromosuccinimide) in the presence of a suitable catalyst. The reaction is typically conducted in a chlorinated solvent under UV light to increase selectivity and yield.

What industries use 3-bromopyridin-2-ol (CAS: 13466-43-8)?

3-Bromopyridin-2-ol (CAS: 13466-43-8) is used in pharmaceuticals for the synthesis of drug intermediates, in polymers for functionalization, and in sensors and semiconductors for electronic applications. Its reactivity and specific functional group make it valuable in these industries.

What precautions should be taken when handling 3-bromopyridin-2-43-8 (CAS: 13466-43-8)?

When handling 3-bromopyridin-2-ol (CAS: 13466-43-8), use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Ensure the use of a fume hood to minimize inhalation risks. Store in a dry, well-ventilated area away from heat and oxidizing agents. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.