Bromo(2,3-dimethylphenyl)magnesium

Basic Information

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CAS Number

134640-85-0

Molecular Formula

C8H9BrMg

Molecular Weight

209.37 g/mol

Chemical Classification

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

65 °C

SMILES

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Cc1cccc(c1C)[Mg]Br

InChI

InChI=1S/C8H9.BrH.Mg/c1-7-5-3-4-6-8(7)2;;/h3-5H,1-2H3;1H;/q;;+1/p-1

InChIKey

GWICKWUOSJJCNO-UHFFFAOYSA-M

LogP

1.94284

Topological Polar Surface Area

0.0 Å²

Hydrogen Bond Donor/Acceptor

0 / 0

Complexity

178

Safety Information

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Hazard Statement

H225 Highly Flammable liquid and vapor
Flammable liquids

H302 Harmful if swallowed
Acute toxicity, oral

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

H351 Suspected of causing cancer
Carcinogenicity

Synonyms & References

English

2,3-Dimethylphenylmagnesium bromide
2,3-DiMethylphenylMagnesiuM broMide, 0.5M in 2-MeTHF
2,3-DiMethylphenylMagnesiuM broMide, 0.5M solution in THF, AcroSeal
magnesium,1,2-dimethylbenzene-6-ide,bromide

MDL Number

MFCD01311494

Customs Code

29310099

FAQ

What are the physical and chemical properties of Bromo(2,3-dimethylphenyl)magnesium (CAS: 134640-85-0)?

Bromo(2,3-dimethylphenyl)magnesium is a liquid at room temperature with a molecular weight of approximately 195.07 g/mol. It is poorly soluble in water but readily soluble in organic solvents like benzene and toluene. The compound is highly reactive, particularly with halides and carbonyls. It is also known for its strong basic properties and can react with acids to form magnesium salts.

How is Bromo(2,3-dimethylphenyl)magnesium (CAS: 134640-85-0) typically synthesized?

Bromo(2,3-dimethylphenyl)magnesium is commonly synthesized via the Grignard reaction. Typically, bromobenzene or bromo-2,3-dimethylbenzene is reacted with magnesium in an ether solvent. The reaction requires careful control of temperature and the use of a drying agent to prevent water from reacting with the magnesium. The product is a colorless or pale yellow liquid.

What industries use Bromo(2,3-dimethylphenyl)magnesium (CAS: 134640-85-0)?

Bromo(2,3-dimethylphenyl)magnesium is primarily used in the organic synthesis of complex molecules. It is a versatile reagent in pharmaceuticals, where it helps in the synthesis of drugs. In the polymer industry, it is used for the preparation of certain types of polymers. Additionally, it has applications in the production of sensors and semiconductors due to its reactivity with a variety of functional groups.

What precautions should be taken when handling Bromo(2,3-dimethylphenyl)magnesium (CAS: 134640-85-0)?

Bromo(2,3-dimethylphenyl)magnesium should be handled with extreme care due to its extreme reactivity. It is flammable and can react violently with water, releasing hydrogen gas. Personal protective equipment (PPE) including safety goggles, gloves, and a lab coat is essential. Work should be carried out in a well-ventilated fume hood. Spills should be handled using appropriate absorbent materials and disposed of according to local hazardous waste regulations. Safety data sheets (SDS) should be consulted for detailed handling instructions.