Epoxomicin | CAS No. 134381-21-8

Epoxomicin

Basic Information

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CAS Number

134381-21-8

Molecular Formula

C28H50N4O7

Molecular Weight

554.73 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

107-109°

Specific Rotation

D24.5 -66.1 ± 0.4° (c = 0.5 in MeOH)

SMILES

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CCC(C)C(C(=O)NC(C(C)O)C(=O)NC(CC(C)C)C(=O)C1(CO1)C)NC(=O)C(C(C)CC)N(C)C(=O)C

InChI

InChI=1S/C28H50N4O7/c1-11-16(5)21(30-27(38)23(17(6)12-2)32(10)19(8)34)25(36)31-22(18(7)33)26(37)29-20(13-15(3)4)24(35)28(9)14-39-28/h15-18,20-23,33H,11-14H2,1-10H3,(H,29,37)(H,30,38)(H,31,36)/t16-,17-,18+,20-,21-,22-,23-,28+/m0/s1

InChIKey

DOGIDQKFVLKMLQ-JTHVHQAWSA-N

LogP

1.1648000000000047

Topological Polar Surface Area

157.44000000000003 Å²

Hydrogen Bond Donor/Acceptor

4 / 11

Complexity

895

Synonyms & References

English

epoxomicin
EX-A1663
N-Acetyl-N-methyl-L-isoleucyl-L-isoleucyl-N-(3-methyl-1-((2-methyloxiranyl)carbonyl)butyl)-L-threoninamide
BU-4061T
DTXSID5044073
BU 4061T
Y-100034
(2R,3S)-2-[acetyl(methyl)amino]-N-[(2S,3S)-1-{[(2S,3R)-3-hydroxy-1-({(2S)-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-2-yl}amino)-1-oxobutan-2-yl]amino}-3-methyl-1-oxopentan-2-yl]-3-methylpentanamide
MFCD03791061
SCHEMBL73907
N-acetyl-N-methyl-L-isoleucyl-L-isoleucyl-N-{(2S)-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-2-yl}-L-threoninamide
CHEBI:42265
(2S,3S)-N-[(1S,2R)-2-hydroxy-1-{[(2S)-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-2-yl]carbamoyl}propyl]-3-methyl-2-[(2S,3S)-3-methyl-2-(N-methylacetamido)pentanamido]pentanamide
CS-3998
MS-30118
NCGC00389337-01
Epoxomicin, >=95% (HPLC), solid
Epoxomicin solution
AKOS025396426
NCGC00485955-01
BU-4061T,Aids010837
N-acetyl-N-methyl-L-isoleucyl-L-isoleucyl-N-((1S)-3-methyl-1-(((2R)-2-methyl-2-oxiranyl)carbonyl)butyl)-L-threoninamide
EPOXOMICIN [MI]
UNII-Y0900I3U8U
BCP13740
Y0900I3U8U
EPOXOMYCIN
L-threoninamide, N-acetyl-N-methyl-L-isoleucyl-L-isoleucyl-N-((1S)-3-methyl-1-(((2R)-2-methyl-2-oxiranyl)carbonyl)butyl)-
Q5383826
134381-21-8
(2S,3S)-2-[[(2S,3S)-2-[acetyl(methyl)amino]-3-methylpentanoyl]amino]-N-[(2S,3R)-3-hydroxy-1-[[(2S)-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-2-yl]amino]-1-oxobutan-2-yl]-3-methylpentanamide

MDL Number

MFCD03791061

FAQ

What is Epoxomicin (CAS: 134381-21-8)?

Epoxomicin is a cyclic depsipeptide antibiotic with potent antitumor activity. It is a compound with a unique chemical structure, consisting of a nitrogen-containing heterocyclic ring and a cyclic peptide. Epoxomicin exhibits a broad spectrum of antimicrobial activity, particularly against multidrug-resistant bacteria.

What are the main uses of Epoxomicin (CAS: 134381-21-8)?

Epoxomicin is primarily used in research for its potent antitumor and antimicrobial properties. It is also studied in clinical trials for its potential as an anticancer agent. Due to its broad spectrum of activity and low toxicity profile, it has gained attention in the pharmaceutical and biotechnology industries.

Is Epoxomicin (CAS: 134381-21-8) safe?

Epoxomicin is generally considered safe when used according to recommended protocols in controlled environments. However, it is important to follow all safety guidelines, including the use of appropriate personal protective equipment and proper handling techniques to minimize exposure. Always consult the Material Safety Data Sheet (MSDS) for detailed safety information.

How should Epoxomicin (CAS: 134381-21-8) be stored?

Epoxomicin should be stored in a cool, dry place away from direct sunlight and heat sources. Maintain a temperature range of 2-8°C (36-46°F) to preserve its stability. Store in a tightly sealed container to protect it from moisture and contaminants. Avoid contact with incompatible materials and keep the substance segregated from strong acids and bases.