5-(Chloromethyl)-4-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one | CAS No. 1338226-21-3
5-(Chloromethyl)-4-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one
Basic Information
CAS Number
1338226-21-3
Molecular Formula
C4H6ClN3O
Molecular Weight
147.57 g/mol
AD
Chemical Classification
Basic Physical Properties
Safety Information
View Safety InformationHazard Statement
H302
Harmful if swallowed
Acute toxicity, oral
Acute toxicity, oral
H315
Causes skin irritation
Skin corrosion/irritation
Skin corrosion/irritation
H319
Causes serious eye irritation
Serious eye damage/eye irritation
Serious eye damage/eye irritation
H332
Harmful if inhaled
Acute toxicity, inhalation
Acute toxicity, inhalation
H335
May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Synonyms & References
English
- 3-(Chloromethyl)-4-methyl-1H-1,2,4-triazol-5(4H)-one
- 5-(chloromethyl)-4-methyl-2H-1,2,4-triazol-3(4H)-one
- MK1439
- 3-(chloromethyl)-4-methyl-4,5-dihydro-1H-1,2,4-triazol-5-one
- 3-(chloromethyl)-4-methyl-1H-1,2,4-triazol-5-one
- 5-(chloromethyl)-4-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one
- FFJXSRWDORQRPQ-UHFFFAOYSA-N
- SB18023
- FCH1658344
- 5-(Chloromethyl)-2,4-dihydro-4-methyl
- AK162299
- AX8229205
MDL Number
MFCD22741615
FAQ
What are the physical and chemical properties of 5-(Chloromethyl)-4-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS: 1338226-21-3)?
5-(Chloromethyl)-4-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one is a solid compound with a molecular weight of approximately 189.03 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. It exhibits good reactivity, particularly towards nucleophiles and reducing agents. The compound crystallizes in the monoclinic system.
How is 5-(Chloromethyl)-4-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS: 1338213-21-3) typically synthesized?
5-(Chloromethyl)-4-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one is synthesized through the condensation reaction of 4-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one with chloroacetaldehyde. The reaction is typically catalyzed by a strong base such as potassium hydroxide, and it proceeds with good selectivity and moderate yield.
What industries use 5-(Chloromethyl)-4-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS: 1338226-21-3)?
5-(Chloromethyl)-4-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one is primarily used in the pharmaceutical and chemical industries for its reactive functional groups. It also finds applications in the synthesis of new materials and as a reagent in organic chemistry.
What precautions should be taken when handling 5-(Chloromethyl)-4-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS: 1338226-21-3)?
When handling 5-(Chloromethyl)-4-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbent materials, and the area should be thoroughly cleaned. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
You might also like
Compound Q&A
What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?
6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...
21889-89-46-Methyl-7-oxabicycl...
Compound Q&A
What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?
4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...
906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A
What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?
2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...
49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A
What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?
2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...
24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A
What is 2-Oxopropanamide (CAS: 631-66-3)?
2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...
631-66-32-Oxopropanamide
Compound Q&A
What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?
2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...
1289040-88-52-Methyl-2-propanyl ...
Compound Q&A
What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?
NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...
2241019-57-6NAMPT inhibitor-link...
Compound Q&A
What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?
It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...
1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A
What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?
1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...
794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A
What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?
Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...
1314981-48-0Vinyl(chloromethyl)d...
