Doravirine | CAS No. 1338225-97-0

Doravirine

Basic Information

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CAS Number

1338225-97-0

Molecular Formula

C17H11ClF3N5O3

Molecular Weight

425.75 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Solubility

Insuluble (6.4E-3 g/L) (25 ºC),

SMILES

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CN1C(=NNC1=O)CN2C=CC(=C(C2=O)OC3=CC(=CC(=C3)C#N)Cl)C(F)(F)F

InChI

InChI=1S/C17H11ClF3N5O3/c1-25-13(23-24-16(25)28)8-26-3-2-12(17(19,20)21)14(15(26)27)29-11-5-9(7-22)4-10(18)6-11/h2-6H,8H2,1H3,(H,24,28)

InChIKey

ZIAOVIPSKUPPQW-UHFFFAOYSA-N

Complexity

860

Synonyms & References

English

3-chloro-5-[1-[(4-methyl-5-oxo-1h-1,2,4-triazol-3-yl)methyl]-2-oxo-4-(trifluoromethyl)pyridin-3-yl]oxybenzonitrile
CHEMBL2364608
Doravirine
MK1439
SureCN2509885
3-Chloro-5-((1-((4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl)-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl)oxy)benzonitrile
3-Chloro-5-({1-[(4-Methyl-5-Oxo-4,5-Dihydro-1h-1,2,4-Triazol-3-Yl)methyl]-2-Oxo-4-(Trifluoromethyl)-1,2-Dihydropyridin-3-Yl}oxy)benzonitrile
MK-1439
Doravirine [USAN]
3-chloro-5-((1-((4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl)-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl)oxy)benzonitrile
D10624
Doravirine (MK-1439)?
AKOS030528603
Pifeltro
F53303
3-Chloro-5-((1-((4-methyl-5-oxo-4,5-dihydro-1H -1,2,4-triazol-3-yl)methyl)-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl)oxy)benzonitrile
DELSTRIGO COMPONENT DORAVIRINE
3-chloro-5-[[1-[(4-methyl-5-oxo-1H-1,2,4-triazol-3-yl)methyl]-2-oxo-4-(trifluoromethyl)-3-pyridyl]oxy]benzonitrile
Doravirine (MK-1439)
1338225-97-0
Pifeltro (TN)
DORAVIRINE [ORANGE BOOK]
HY-16767
Doravirine [USAN:INN]
Q6885419
4ncg
BDBM50508293
s6492
Doravirinum
DORAVIRINE [MI]
MS-27504

MDL Number

MFCD22417167

FAQ

What is Doravirine (CAS: 1338225-97-0)?

Doravirine (CAS: 1338225-97-0) is an antiretroviral drug used in the treatment of HIV-1 infection. It is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that works by inhibiting the enzyme reverse transcriptase, which is essential for the replication of the HIV virus.

What are the main uses of Doravirine (CAS: 1338225-97-0)?

Doravirine (CAS: 1338225-97-0) is primarily used in the treatment of human immunodeficiency virus-1 (HIV-1) infection. It is included in combination therapy to inhibit the replication of the virus in patients who are either treatment-naive or have developed resistance to other antiretroviral drugs.

Is Doravirine (CAS: 1338225-97-0) safe?

Doravirine (CAS: 1338225-97-0) is generally considered safe when used as prescribed. However, like all medications, it may cause side effects such as headache, nausea, and dizziness. Users should consult their healthcare providers for detailed safety information and follow their advice on usage.

How should Doravirine (CAS: 1338225-97-0) be stored?

Doravirine (CAS: 1338225-97-0) should be stored at room temperature, between 15-30°C (59-86°F). It should be protected from light and kept in a tightly sealed container. Avoid exposure to moisture and direct sunlight, as these can affect the stability of the medication.