2-Chloro-4-methyl-3-pyridinamine

Basic Information

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CAS Number

133627-45-9

Molecular Formula

C6H7ClN2

Molecular Weight

142.59 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

65-70 °C

Density

1.2600

SMILES

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CC1=C(C(=NC=C1)Cl)N

InChI

InChI=1S/C6H7ClN2/c1-4-2-3-9-6(7)5(4)8/h2-3H,8H2,1H3

InChIKey

UOBCYTOUXLAABU-UHFFFAOYSA-N

LogP

1.6256199999999998

Topological Polar Surface Area

38.91 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

97.1

Safety Information

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GHS Hazard Pictograms

H302

H315

H318

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

HMS1699O14
EN300-92109
A806652
2-chloro-4-methylpyridin-3-amine
NS00125734
2-Chloro-3-amino-4-picoline
3-PYRIDINAMINE, 2-CHLORO-4-METHYL-
BCP22201
FT-0657862
PS-6265
PB21708
3-Amino-2-chloro-4-methylpyridine, 97%
W-205427
CS-W008207
2-Chloro-3-amino-4-methylpyridine
SCHEMBL1223407
2-chloro-4-methyl-pyridin-3-amine;2-Chloro-3-amino-4-methylpyridine
AM20070273
2-Chloro-4-methyl-pyridin-3-ylamine
3-amino-2-chloro-4-methyl pyridine
DTXSID30373350
FT-0643202
MFCD00673152
(2-METHOXY-BIPHENYL-4-YL)-ACETICACID
3-amino-2-chloro-4-methyl-pyridine
UOBCYTOUXLAABU-UHFFFAOYSA-N
AC-1144
2-chloro-4-methyl-3-pyridinamine
133627-45-9
AKOS000301676
SB10595

MDL Number

MFCD00673152

Customs Code

2933399090

FAQ

What is 2-Chloro-4-methyl-3-pyridinamine (CAS: 133627-45-9)?

2-Chloro-4-methyl-3-pyridinamine (CAS: 133627-45-9) is a substituted pyridinamine derivative with the chemical formula C6H7ClN. It features a pyridine ring with a chlorine atom at position 2, a methyl group at position 4, and an amino group at position 3. This compound is known for its reactivity and is commonly used in organic synthesis. Its structural characteristics make it a valuable intermediate in pharmaceutical and chemical research.

What are the main uses of 2-Chloro-4-methyl-3-pyridinamine (CAS: 133627-45-9)?

2-Chloro-4-methyl-3-pyridinamine (CAS: 133627-45-9) is primarily utilized in pharmaceutical synthesis as a precursor for developing drugs targeting neurological disorders. It also finds applications in industrial chemistry for producing agrochemicals and specialty materials. In research settings, it serves as a key compound for studying nitrogen-containing heterocycles. Its versatility in chemical reactions makes it relevant across multiple sectors, including drug discovery and organic synthesis.

Is 2-Chloro-4-methyl-3-pyridinamine (CAS: 133627-45-9) safe?

2-Chloro-4-methyl-3-pyridinamine (CAS: 133627-45-9) requires careful handling due to potential toxicity. It may irritate skin, eyes, and respiratory systems, so proper personal protective equipment (PPE) is essential. Safety standards emphasize avoiding inhalation, ingestion, or contact with the compound. Always consult safety data sheets (SDS) for specific guidelines and ensure controlled environments to minimize health risks.

How should 2-Chloro-4-methyl-3-pyridinamine (CAS: 133627-45-9) be stored?

2-Chloro-4-methyl-3-pyridinamine (CAS: 133627-45-9) should be stored in a cool, dry place (below 25°C), away from light, and in airtight containers to prevent moisture exposure. It is sensitive to humidity and air, so desiccants may be required. Storage conditions should maintain chemical stability, and the container should be made of inert materials to avoid reactions. Always follow recommended safety and handling protocols for storage.