2-[2-(1-Piperazinyl)ethoxy]ethanol

Basic Information

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CAS Number

13349-82-1

Molecular Formula

C8H18N2O2

Molecular Weight

174.24 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

172°C/10mmHg

Refractive Index

n20/D 1.497(lit.)

Vapor Pressure

0.0±1.4 mmHg at 25°C

SMILES

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C1CN(CCN1)CCOCCO

InChI

InChI=1S/C8H18N2O2/c11-6-8-12-7-5-10-3-1-9-2-4-10/h9,11H,1-8H2

InChIKey

FLNQAPQQAZVRDA-UHFFFAOYSA-N

LogP

-1.0994999999999986

Topological Polar Surface Area

44.730000000000004 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

105

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

1-[2-(2-Hydroxyethoxy)ethyl]piperazine
A25084
1-[2-(2-Hydroxyethoxy)ethyl]piperazine, 95%
4-[2-(2-hydroxy-ethoxy)-ethyl]-piperazine
2-[2-(1-Piperazinyl)ethoxy]ethanol #
AS-10842
2-[2-(piperazin-1-yl)ethoxy]ethanol
2-[2-(piperazin-1-yl)ethoxy]ethan-1-ol
AM20080240
EC 700-022-7
Ethanol, 2-[2-(1-piperazinyl)ethoxy]-
1-Hydroxyethoxyethylpiperazine
GEO-01513
NS00001293
1-[2-(2-hydroxyethoxyl)ethyl]piperizine
2-(2-(Piperazin-1-yl)ethoxy)ethanol
SY021202
n-hydroxyethoxyethylpiperazine
2-(2-piperazin-1-ylethoxy)ethanol
WWT5E4KNO3
CHEBI:151027
2-(2-piperazin-1-yl-ethoxy)-ethanol
1-[2-(hydroxyethoxy)-ethyl]-piperazine
ETHANOL, 2-(2-(1-PIPERAZINYL)ETHOXY)-
1-(2-(2-Hydroxyethoxy)ethyl)piperazine
2-{[2-(1-piperazinyl)ethyl]oxy}ethanol
FT-0607089
J-504793
MFCD00074931
1-(2-(2-Hydroxyethoxy)-ethyl)-piperazine
H1192

MDL Number

MFCD00074931

FAQ

What is 2-[2-(1-Piperazinyl)ethoxy]ethanol (CAS: 13349-82-1)?

2-[2-(1-Piperazinyl)ethoxy]ethanol is an organic compound with the chemical formula C6H14N2O2. It is a clear, colorless liquid with moderate solubility in organic solvents and exhibits hydrophilic properties. This compound is commonly used as a key intermediate in pharmaceutical synthesis due to its structural versatility and reactivity in forming complex molecules.

What are the main uses of 2-[2-(1-Piperazinyl)ethoxy]ethanol (CAS: 13349-82-1)?

The primary applications of 2-[2-(1-Piperazinyl)ethoxy]ethanol include pharmaceutical research, where it serves as a building block for drug development, particularly in antipsychotic and antidepressant compounds. It is also utilized in industrial processes for creating surfactants and in organic chemistry research as a reagent for functional group modifications and polymer synthesis.

Is 2-[2-(1-Piperazinyl)ethoxy]ethanol (CAS: 13349-82-1) safe?

2-[2-(1-Piperazinyl)ethoxy]ethanol is generally considered safe when handled according to standard chemical safety protocols. However, it may have moderate toxicity upon prolonged exposure or ingestion. Protective measures include wearing gloves, goggles, and lab coats, and ensuring proper ventilation. Always follow OSHA and EPA guidelines for safe handling and disposal.

How should 2-[2-(1-Piperazinyl)ethoxy]ethanol (CAS: 13349-82-1) be stored?

Store 2-[2-(1-Piperazinyl)ethoxy]ethanol in a tightly sealed, light-resistant container at room temperature (15-25°C). Keep it away from moisture and direct light to maintain stability. Ensure storage in a well-ventilated area, and avoid exposure to incompatible substances. Use glass or HDPE containers for optimal preservation.