Methyl 2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoate | CAS No. 1332524-01-2

Methyl 2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoate

Basic Information

CAS Number

1332524-01-2

Molecular Formula

C13H17FN2O3

Molecular Weight

268.29 g/mol

AD

Basic Physical Properties

Boiling Point

381 ºC

Flash Point

184 ºC

CC(C)(C(=O)OC)NC1=CC(=C(C=C1)C(=O)NC)F

InChI

InChI=1S/C13H17FN2O3/c1-13(2,12(18)19-4)16-8-5-6-9(10(14)7-8)11(17)15-3/h5-7,16H,1-4H3,(H,15,17)

InChIKey

MLHUTKWFDCMHQO-UHFFFAOYSA-N

LogP

1.5488

Topological Polar Surface Area

67.42999999999999 Ų

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

347

Synonyms & References

English

  • N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine Methyl Ester
  • Methyl 2-((3-fluoro-4-(methylcarbamoyl)-phenyl)amino)-2-methylpropanoate
  • Methyl 2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoate
  • methyl 2-[3-fluoro-4-(methylcarbamoyl)anilino]-2-methyl-propanoat e
  • N-[3-fluoro-4-[(methylamino)carbonyl]phenyl]-2-methyl-Alanine methyl ester
  • 1,1-Dimethyl-4-(2-carbomethoxyphenyl)-3-thiosemicarbazide
  • 1,1-Dimethyl-4-(o-(methoxycarbonyl)phenyl)-3-thiosemicarbazide
  • methyl 2(3'-dimethylaminothioureido)benzoate
  • methyl 2-(3-fluoro-4-(methylcarbamoyl)phenylamino)-2-methylpropanoate
  • Semicarbazide,1,1-dimethyl-4-(o-(methoxycarbonyl)phenyl)-3-thio
  • MLHUTKWFDCMHQO-UHFFFAOYSA-N
  • BCP14593
  • 3816AH
  • AK158354
  • AX8292159
  • ST24047592
  • methyl 2-[3-fluoro-4-(methylcarbamoyl)anilino]-2-methylpropanoate
  • methyl 2-[3-f
  • Methyl2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoate
  • 2CQV7V48AN
  • 2-(3-Fluoro-4-methylcarbamoyl-phenylamino)-2-methyl-propionic acid methyl ester
  • 1332524-01-2
  • CS-13235
  • N-(3-Fluoro-4-((methylamino)carbonyl)phenyl)-2-methylalanine methyl ester
  • CS-M2261
  • HY-I0125
  • AKOS024262442
  • SY275445
  • Alanine, N-[3-fluoro-4-[(methylamino)carbonyl]phenyl]-2-methyl-, methyl ester
  • DB-361307
  • N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine methyl ester

MDL Number

MFCD22581652

FAQ

What are the physical and chemical properties of Methyl 2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoate (CAS: 1332524-01-2)?

Methyl 2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoate is a solid crystalline compound with a molecular weight of approximately 313.35 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and dichloromethane. The compound is reactive towards acidic and basic conditions. It is stable under normal laboratory conditions but should be stored in a dry, cool place away from direct sunlight.

How is Methyl 2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoate (CAS: 1332524-01-2) typically synthesized?

Methyl 2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoate is typically synthesized through a multi-step process involving the coupling of a fluoroaniline derivative with a methyl isocyanate followed by an amide formation reaction. The process is conducted under mild conditions, using appropriate catalysts to enhance selectivity and yield. The final product is isolated and purified using standard techniques such as recrystallization.

What industries use Methyl 2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoate (CAS: 1332524-01-2)?

Methyl 2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoate is used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the chemical industry as an intermediate in the production of other chemical compounds. Its use in sensors and semiconductors is also being explored, although it is less common in these applications compared to its use in pharmaceuticals and chemical synthesis.

What precautions should be taken when handling Methyl 2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoate (CAS: 1332524-01-2)?

When handling Methyl 2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoate, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to minimize exposure to fumes. Spills should be cleaned up immediately using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed information on handling, storage, and disposal procedures.

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