2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide

Basic Information

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CAS Number

13311-84-7

Molecular Formula

C11H11F3N2O3

Molecular Weight

276.21 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

110.0 to 114.0 deg-C

Boiling Point

400.3°C at 760 mmHg

Flash Point

195.9±28.7 °C

Refractive Index

1.477

SMILES

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CC(C)C(=O)NC1=CC(=C(C=C1)[N+](=O)[O-])C(F)(F)F

InChI

InChI=1S/C11H11F3N2O3/c1-6(2)10(17)15-7-3-4-9(16(18)19)8(5-7)11(12,13)14/h3-6H,1-2H3,(H,15,17)

InChIKey

MKXKFYHWDHIYRV-UHFFFAOYSA-N

LogP

2.6

Complexity

352

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H361 Suspected of damaging fertility or the unborn child
Reproductive toxicity

H370 Causes damage to organs
Specific target organ toxicity, single exposure

Synonyms & References

English

SR-01000075888-1
MLS001065596
CAS-13311-84-7
FLUTAMIDE [MART.]
SR-01000075888-7
Spectrum2_001201
D00586
FT-0626493
CPD000058187
Tox21_110154
NCGC00015452-03
MFCD00072009
alpha,alpha,alpha-trifluoro-2-methyl-4''-nitro-m-propionotoluidide
NSC-757817
Cebatrol, veterinary
Flutamide USP25
BPBio1_000087
NSC-215876
NCGC00015452-09
Flutamida (INN-Spanish)
4''-nitro-3''-trifluoromethylisobutyranilide
AB02835
HMS501G21
SCHEMBL12932289
Q-201131
.alpha.,.alpha.,.alpha.-Trifluoro-2-methyl-4'-nitro-m-propionotoluidide
NFBA
KS-5091
EINECS 236-341-9
HY-B0022
FLUTAMIDE [INN]

MDL Number

MFCD00072009

Customs Code

2924299090

FAQ

What is 2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide (CAS: 13311-84-7)?

2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide (CAS: 13311-84-7) is an organic compound with the chemical formula C10H10F3N2O2. It features an amide functional group attached to a benzene ring substituted with a nitro group and a trifluoromethyl group. The compound is typically a white solid with moderate solubility in organic solvents and is valued for its structural versatility in chemical synthesis.

What are the main uses of 2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide (CAS: 13311-84-7)?

This compound is primarily used in pharmaceutical research as an intermediate for drug development, particularly in the synthesis of anti-inflammatory and antiviral agents. It also finds applications in agrochemicals and materials science due to its reactivity and functional group diversity. Its utility stems from the ability to modify the trifluoromethyl and nitro groups for tailored biological activity.

Is 2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide (CAS: 13311-84-7) safe?

Safety of 2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide (CAS: 13311-84-7) depends on handling conditions. It is classified as a hazardous chemical due to potential skin and respiratory irritation. Precautions include wearing protective gloves, goggles, and a lab coat, and working in a well-ventilated area. Always follow standard safety protocols and consult the Safety Data Sheet (SDS) for specific guidelines.

How should 2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide (CAS: 13311-84-7) be stored?

Store 2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide (CAS: 13311-84-7) in a cool, dry, and dark place, ideally at 2-8°C. Keep it in a sealed, airtight container to prevent moisture absorption and degradation. Avoid exposure to light and air to maintain stability, and ensure storage complies with chemical safety regulations for hazardous substances.