Pentafluorophenyl N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-trityl-L-asparaginate | CAS No. 132388-64-8

Pentafluorophenyl N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-trityl-L-asparaginate

Basic Information

CAS Number

132388-64-8

Molecular Formula

C44H31F5N2O5

Molecular Weight

762.73 g/mol

AD

Basic Physical Properties

Specific Rotation

-7 º (c=1 in dioxane)

c1ccc(cc1)C(c2ccccc2)(c3ccccc3)NC(=O)C[C@@H](C(=O)Oc4c(c(c(c(c4F)F)F)F)F)NC(=O)OCC5c6ccccc6-c7c5cccc7

InChI

InChI=1S/C44H31F5N2O5/c45-36-37(46)39(48)41(40(49)38(36)47)56-42(53)34(50-43(54)55-25-33-31-22-12-10-20-29(31)30-21-11-13-23-32(30)33)24-35(52)51-44(26-14-4-1-5-15-26,27-16-6-2-7-17-27)28-18-8-3-9-19-28/h1-23,33-34H,24-25H2,(H,50,54)(H,51,52)/t34-/m0/s1

InChIKey

YSONQVIVMGOLBG-UMSFTDKQSA-N

LogP

8.693200000000003

Topological Polar Surface Area

93.73 Ų

Hydrogen Bond Donor/Acceptor

2 / 7

Complexity

1240

Synonyms & References

English

  • (S)-Perfluorophenyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-oxo-4-(tritylamino)butanoate
  • N-alpha-(9-fluorenylmethyloxycarbonyl)-N-beta-trityl-L-asparagine pentafluorphenyl ester
  • Fmoc-Asn(Trt)-Opfp
  • (2,3,4,5,6-pentafluorophenyl) (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-4-(tritylamino)butanoate
  • (S)-Perfluorophenyl 2-((((9H-fluoren-9-yl)methoxy)-carbonyl)amino)-4-oxo-4-(tritylamino)butanoate
  • Fmoc-L-Asn(Trt)-Opfp
  • H-Ile-NH2•HCl
  • Pentafluorophenyl N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-trityl-L-asparaginate
  • A-trityl-L-asparagine pentafluorophenyl ester
  • Fmoc-Asn(Trt) pentafluorophenyl ester
  • N-Fmoc-N'-trityl-L-asparagine pentafluorophenyl ester
  • pentafluorophenyl ester
  • FMOC-ASPARAGINE(TRT)-OPFP
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl Asn(Trt)-Opfp
  • FMOC-N-BETA-TRITYL-L-ASPARAGINE PENTAFLUOROPHENYL ESTER
  • N-α-Fmoc-N-β-trityl-L-asparagine pentafluorophenyl ester
  • FMOC-N-GAMMA-TRITYL-L-ASPARAGINE PENTAFLUOROPHENYL ESTER
  • N-alpha-FMoc-beta-trityl-L-asparagine pentafluorophenyl ester
  • N-ALPHA-FMOC-N-BETA-TRITYL-L-ASPARAGINE PENTAFLUORPHENYL ESTER
  • N-alpha-Fmoc-N-beta-trityl-L-asparagine pentafluorophenyl ester
  • YSONQVIVMGOLBG-UMSFTDKQSA-N
  • (S)-perfluorophenyl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-4-oxo-4-(tritylamino)
  • (S)-perfluorophenyl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-4-oxo-4-(tritylamino)butanoate
  • 388F648
  • FMOC-N-BETA-TRITYL-L-ASPARAGINE PENTAFLUOROPHENYL
  • Pentafluorophenyl N~2~-{[(9H-fluoren-9-yl)methoxy]carbonyl}-N-(trip

MDL Number

MFCD00153373

FAQ

What is Pentafluorophenyl N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-trityl-L-asparaginate (CAS: 132388-64-8)?

Pentafluorophenyl N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-trityl-L-asparaginate is a complex organic compound used in pharmaceutical research. It contains a pentafluorophenyl group and a trityl group, making it useful as a protecting group in peptide synthesis.

What are the main uses of Pentafluorophenyl N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-trityl-L-asparaginate (CAS: 132388-64-8)?

This compound is primarily used as a protecting group in the synthesis of peptides, particularly in drug discovery and development. It is valuable for its ability to protect the asparaginate functionality during chemical modifications.

Is Pentafluorophenyl N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-trityl-L-asparaginate (CAS: 132388-64-8) safe?

While generally safe under controlled laboratory conditions, this compound should be handled with caution. It is essential to follow all safety guidelines, including wearing appropriate personal protective equipment and ensuring proper ventilation.

How should Pentafluorophenyl N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-trityl-L-asparaginate (CAS: 132388-64-8) be stored?

Store this compound in a cool, dark place, away from direct sunlight. Maintain it at a temperature below 20°C and keep it in a tightly sealed container to prevent degradation. Humidity levels should be kept low to avoid moisture absorption.

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