N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-trityl-L-asparagine

Basic Information

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CAS Number

132388-59-1

Molecular Formula

C38H32N2O5

Molecular Weight

596.68 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

201-204 °C

Boiling Point

858.1 oC at 760 mmHg

Density

1.2710

Flash Point

472.8oC

Solubility

<0.00005g/l

Refractive Index

-19 ° (C=1, DMF)

Specific Rotation

-16 º (c=1, MeOH)

SMILES

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C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)NC(=O)CC(C(=O)O)NC(=O)OCC4C5=CC=CC=C5C6=CC=CC=C46

InChI

InChI=1S/C38H32N2O5/c41-35(40-38(26-14-4-1-5-15-26,27-16-6-2-7-17-27)28-18-8-3-9-19-28)24-34(36(42)43)39-37(44)45-25-33-31-22-12-10-20-29(31)30-21-11-13-23-32(30)33/h1-23,33-34H,24-25H2,(H,39,44)(H,40,41)(H,42,43)/t34-/m0/s1

InChIKey

KJYAFJQCGPUXJY-UMSFTDKQSA-N

LogP

6.476700000000006

Topological Polar Surface Area

104.73 Å²

Hydrogen Bond Donor/Acceptor

3 / 7

Complexity

931

Safety Information

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GHS Hazard Pictograms

H413

Hazard Statement

H413 May cause long lasting harmful effects to aquatic life
Hazardous to the aquatic environment, long-term hazard

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

KJYAFJQCGPUXJY-UMSFTDKQSA-N
N2-(((9H-fluoren-9-yl)methoxy)carbonyl)-N4-trityl-L-asparagine
5R94765WYL
F0508
Nalpha-(9-Fluorenylmethoxycarbonyl)-Ngamma-trityl-L-asparagine
N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-beta-trityl-L-asparagine
2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-oxo-4-(tritylamino)butanoic acid, (2S)-
AKOS015924190
DTXSID80348710
AS-12974
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-oxo-4-(tritylamino)butanoic acid
Nalpha-Fmoc-Ngamma-trityl-L-asparagine
J-300051
N-Fmoc-N4-trityl-L-Asparagine
(2S)-2-([[(9H-Fluoren-9-yl)methoxy]carbonyl]amino)-3-[(triphenylmethyl)carbamoyl]propanoic acid
Fmoc-Asn(Trt)-OH, >=97.0% (sum of enantiomers, HPLC)
BP-20376
HY-W002327
Nalpha-[(9H-Fluoren-9-ylmethoxy)carbonyl]-Ngamma-trityl-L-asparagine
M03352
N-Alpha-Fmoc-N-beta-trityl-L-asparagine
N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-(triphenylmethyl)-L-asparagine
SCHEMBL118112
Fmoc-Asn(Trt)-OH (U-13C4, U-15N2)
J-006492
CS-W002327
Fmoc-L-Asn(Trt)-OH
N2-Fmoc-N4-trityl-L-asparagine
(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-[(triphenylmethyl)carbamoyl]propanoic acid
AC-11089
MFCD00077049

MDL Number

MFCD00077049

Customs Code

2924299090

FAQ

What is N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-trityl-L-asparagine (CAS: 132388-59-1)?

N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-trityl-L-asparagine (CAS: 132388-59-1) is a protected derivative of L-asparagine, commonly used in organic synthesis and pharmaceutical research. It contains a fluorenylmethoxy carbonyl (Fmoc) group and a trityl protecting group, making it suitable for controlled peptide assembly. Its chemical formula is C26H26N2O6, and it is typically a white solid with good solubility in organic solvents.

What are the main uses of N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-trityl-L-asparagine (CAS: 132388-59-1)?

N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-trityl-L-asparagine (CAS: 132388-59-1) is primarily used in the synthesis of peptides and peptidomimetics, especially in solid-phase peptide synthesis (SPPS). It serves as a building block for drug development and is also utilized in research for studying amino acid derivatives and their chemical behavior. Its structural features make it valuable in creating complex organic molecules.

Is N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-trityl-L-asparagine (CAS: 132388-59-1) safe?

N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-trityl-L-asparagine (CAS: 132388-59-1) is generally considered safe when handled properly. It is not classified as toxic under normal conditions, but as with any chemical, it should be treated with care. Protective measures such as gloves, goggles, and a well-ventilated workspace are recommended. Always follow safety guidelines for chemical handling and disposal.

How should N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-trityl-L-asparagine (CAS: 132388-59-1) be stored?

N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-trityl-L-asparagine (CAS: 132388-59-1) should be stored in a cool, dry, and dark place to maintain its stability. It is best kept in a sealed container at a temperature below 25°C and away from moisture and light. Proper storage ensures the compound remains chemically stable and effective for use in research and synthesis applications.