2-Methoxyethyl (2E)-3-phenyl-2-propen-1-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate

Basic Information

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CAS Number

132203-70-4

Molecular Formula

C27H28N2O7

Molecular Weight

492.5 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Physical State

Powder

Melting Point

108.0 to 112.0 deg-C

Boiling Point

652.6°C at 760 mmHg

Density

1.24

Flash Point

348.5oC

Solubility

H2O: ≤2mg/mL

Refractive Index

1.581

SMILES

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CC1=C(C(C(=C(N1)C)C(=O)OCC=CC2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OCCOC

InChI

InChI=1S/C27H28N2O7/c1-18-23(26(30)35-14-8-11-20-9-5-4-6-10-20)25(21-12-7-13-22(17-21)29(32)33)24(19(2)28-18)27(31)36-16-15-34-3/h4-13,17,25,28H,14-16H2,1-3H3/b11-8+

InChIKey

KJEBULYHNRNJTE-DHZHZOJOSA-N

LogP

5.12780

Complexity

896

Safety Information

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GHS Hazard Pictograms

H318

Hazard Statement

H318 Causes serious eye damage
Serious eye damage/eye irritation

Sensitiveness

对光敏感

Toxicity

LD50 in male, female mice, rats (mg/kg): 5000, 5000, 5000, 4412 orally; 5000 all species s.c.; 1845, 2353, 441, 426 i.p. (Wada)

Synonyms & References

English

2-methoxyethyl-3-phenyl-2-propen-1-yl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate
Cinalong
Cilnidipine, >=98% (HPLC), powder
CHEMBL452076
118934-76-2
s1293
132203-70-4
HY-17404
KS-1294
CILNIDIPINE [MART.]
DB09232
CCG-221188
DTXSID0046309
Siscard
(E)-Cinnamyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate
132295-21-7
Atelec (TN)
HMS3884K09
J-006141
3-cinnamyl 5-(2-methoxyethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
SCHEMBL25550
CILNIDIPINE [JAN]
Cinaldipine
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-methoxyethyl 3-phenyl-2-propenyl ester, (E)-(+-)-
CS-1133
Cilnidipine, (-)-
Cilnidipine (JP17/INN)
FRC-8653
UNII-4LNU2SU262
2-methoxyethyl (2E)-3-phenylprop-2-en-1-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
F2173-0669

MDL Number

MFCD00865853

Customs Code

2933399090

FAQ

What is 2-Methoxyethyl (2E)-3-phenyl-2-propen-1-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate (CAS: 132203-70-4)?

2-Methoxyethyl (2E)-3-phenyl-2-propen-1-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate (CAS: 132203-70-4) is a complex organic compound used primarily in chemical synthesis. It contains a pyridine ring with substituents, a methoxyethyl group, and a phenyl-substituted propenyl chain. The compound is known for its structural versatility and potential applications in pharmaceutical and research settings.

What are the main uses of 2-Methoxyethyl (2E)-3-phenyl-2-propen-1-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate (CAS: 132203-70-4)?

This compound is mainly used in pharmaceutical research for the synthesis of various bioactive molecules. It also finds applications in organic chemistry for developing new materials and as a reagent in complex chemical reactions. Its unique structure makes it valuable in the design of drug molecules and functional compounds.

Is 2-Methoxyethyl (2E)-3-phenyl-2-propen-1-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate (CAS: 132203-70-4) safe?

As with many chemical compounds, safety depends on handling conditions. It is recommended to use appropriate personal protective equipment (PPE) such as gloves and goggles when working with this substance. While specific toxicity data may be limited, it is generally considered safe when used in controlled environments and in compliance with standard chemical safety protocols.

How should 2-Methoxyethyl (2E)-3-phenyl-2-propen-1-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate (CAS: 132203-70-4) be stored?

The compound should be stored in a cool, dry, and well-ventilated area, away from light and moisture. It is best kept in a sealed, inert container at a temperature below 25°C. Avoid exposure to air and ensure storage conditions maintain its chemical stability and integrity over time.