D-Histidyl-L-cysteinyl-L-leucylglycyl-L-lysyl-L-tryptophyl-L-leucylglycyl-L-histidyl-L-prolyl-L-alpha-aspartyl-L-lysyl-L-phenylalanine | CAS No. 131334-43-5

D-Histidyl-L-cysteinyl-L-leucylglycyl-L-lysyl-L-tryptophyl-L-leucylglycyl-L-histidyl-L-prolyl-L-alpha-aspartyl-L-lysyl-L-phenylalanine

Basic Information

CAS Number

131334-43-5

Molecular Formula

C72H104N20O16S

Molecular Weight

1537.82 g/mol

AD

Basic Physical Properties

CC(C)CC(C(=O)NCC(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CC3=CC=CC=C3)C(=O)O)NC(=O)C(CC4=CNC5=CC=CC=C54)NC(=O)C(CCCCN)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(CS)NC(=O)C(CC6=CN=CN6)N

InChI

InChI=1S/C72H104N20O16S/c1-40(2)25-51(63(98)80-36-60(94)84-55(30-45-34-77-39-82-45)71(106)92-24-14-21-58(92)70(105)89-54(31-61(95)96)68(103)85-50(20-11-13-23-74)66(101)90-56(72(107)108)27-42-15-6-5-7-16-42)86-67(102)53(28-43-32-78-48-18-9-8-17-46(43)48)88-65(100)49(19-10-12-22-73)83-59(93)35-79-64(99)52(26-41(3)4)87-69(104)57(37-109)91-62(97)47(75)29-44-33-76-38-81-44/h5-9,15-18,32-34,38-41,47,49-58,78,109H,10-14,19-31,35-37,73-75H2,1-4H3,(H,76,81)(H,77,82)(H,79,99)(H,80,98)(H,83,93)(H,84,94)(H,85,103)(H,86,102)(H,87,104)(H,88,100)(H,89,105)(H,90,101)(H,91,97)(H,95,96)(H,107,108)/t47-,49+,50+,51+,52+,53+,54+,55+,56+,57+,58+/m1/s1

InChIKey

VTBYVGRYDXYLHZ-PWSGYBBZSA-N

LogP

-2.362100000000023

Topological Polar Surface Area

566.2199999999997 Ų

Hydrogen Bond Donor/Acceptor

22 / 36

Complexity

3040

Synonyms & References

English

  • 131334-43-5
  • PLP(139-151)
  • PLP (139-151)
  • H-His-Cys-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe-OH
  • L-Phenylalanine,L-histidyl-L-cysteinyl-L-leucylglycyl-L-lysyl-L-tryptophyl-L-leucylglycyl-L-histidyl-L-prolyl-L-a-aspartyl-L-lysyl-
  • H-HIS-CYS-LEU-GLY-LYS-TRP-LEU-GLY-HIS-PRO-ASP-LYS-PHE-OH
  • HIS-CYS-LEU-GLY-LYS-TRP-LEU-GLY-HIS-PRO-ASP-LYS-PHE
  • Lipophilin (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat)
  • L-Phenylalanine,L-histidyl-L-cysteinyl-L-leucylglycyl-L-lysyl-L-tryptophyl-L-leucylglycyl-L-hi...
  • L-Phenylalanine,L-histidyl-L-cysteinyl-L-leucylglycyl-L-lysyl-L-tryptophyl-L-leucylglycyl-L-histidyl-L-prolyl-L-a-aspartyl-L-
  • Myelin Proteolipid Protein (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat)
  • HCLGKWLGHPDKF
  • MYELIN PROTEOLIPID PROTEIN (139-151)
  • Myelin Proteolipid Protein (139-151) (1)
  • MYELIN PROTEOLIPID PROTEIN (139-151) (HUMAN,BOVINE,DOG,MOUSE,RAT
  • PLP (139-151) (DEPALMITOYLATED) (HUMAN,BOVINE,DOG,MOUSE,RAT)
  • PLP (HUMAN,BOVINE,DOG,MOUSE,RAT)
  • PLP (HUMAN, BOVINE, DOG, MOUSE, RAT)
  • PLP (139-151) (DEPALMITOYLATED) (HUMAN, BOVINE, DOG, MOUSE, RAT)
  • MYELIN PROTEOLIPID PROTEIN (139-151) (HUMAN, BOVINE, DOG, MOUSE, RAT)
  • H-HIS-CYS-LEU-GLY-LYS-TRP-LEU-GLY-HIS-PRO-ASP-LYS-PHE-OH (HUMAN, BOVINE, DOG, MOUSE, RAT)
  • H-DL-His-DL-Cys-DL-Leu-Gly-DL-Lys-DL-Trp-DL-Leu-Gly-DL-His-DL-Pro-DL-Asp-DL-Lys-DL-Phe-OH
  • PLP 139-151
  • HCLGKWLGHPDKF;His-Cys-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe

MDL Number

MFCD06659095

FAQ

What is D-Histidyl-L-cysteinyl-L-leucylglycyl-L-lysyl-L-tryptophyl-L-leucylglycyl-L-histidyl-L-prolyl-L-alpha-aspartyl-L-lysyl-L-phenylalanine (CAS: 131334-43-5)?

D-Histidyl-L-cysteinyl-L-leucylglycyl-L-lysyl-L-tryptophyl-L-leucylglycyl-L-histidyl-L-prolyl-L-alpha-aspartyl-L-lysyl-L-phenylalanine is a complex cyclic peptide. It is known for its unique structure and is used in pharmaceutical research and development.

What are the main uses of D-Histidyl-L-cysteinyl-L-leucylglycyl-L-lysyl-L-tryptophyl-L-leucylglycyl-L-histidyl-L-prolyl-L-alpha-aspartyl-L-lysyl-L-phenylalanine (CAS: 131334-43-5)?

This compound is primarily used in the pharmaceutical industry for research purposes, particularly in drug discovery and development. It has potential applications as a model compound for studying protein-protein interactions and molecular recognition.

Is D-Histidyl-L-cysteinyl-L-leucylglycyl-L-lysyl-L-tryptophyl-L-leucylglycyl-L-histidyl-L-prolyl-L-alpha-aspartyl-L-lysyl-L-phenylalanine (CAS: 131334-43-5) safe?

The safety of this compound depends on the context of use. It is generally safe when handled under appropriate laboratory conditions with proper protective measures, such as gloves and laboratory coats. However, it should be used with caution to avoid skin contact and inhalation.

How should D-Histidyl-L-cysteinyl-L-leucylglycyl-L-lysyl-L-tryptophyl-L-leucylglycyl-L-histidyl-L-prolyl-L-alpha-aspartyl-L-lysyl-L-phenylalanine (CAS: 131334-43-5) be stored?

This compound should be stored in a cool, dry place away from direct sunlight and humidity. It is recommended to store it in a tightly sealed container to prevent degradation. The temperature should be maintained between 2°C and 8°C (35°F to 46°F) to ensure stability.

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