N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(2-thienyl)-L-alanine

Basic Information

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CAS Number

130309-35-2

Molecular Formula

C22H19NO4S

Molecular Weight

393.46 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

218.5 ºC

Boiling Point

623.4℃ at 760 mmHg

Refractive Index

1.5060 (estimate)

SMILES

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C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CC4=CC=CS4)C(=O)O

InChI

InChI=1S/C22H19NO4S/c24-21(25)20(12-14-6-5-11-28-14)23-22(26)27-13-19-17-9-3-1-7-15(17)16-8-2-4-10-18(16)19/h1-11,19-20H,12-13H2,(H,23,26)(H,24,25)/t20-/m0/s1

InChIKey

PXBMQFMUHRNKTG-FQEVSTJZSA-N

LogP

4.282500000000002

Topological Polar Surface Area

75.63 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

549

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

J-005784
s11142
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(thiophen-2-yl)propanoic acid
2-Thiophenepropanoic acid, alpha-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (alphaS)-
AM83780
Fmoc- beta -(2-thienyl)-Ala-OH
DS-15456
(s)-2-(((9h-fluoren-9-yl)methoxy)carbonylamino)-3-(thiophen-2-yl)propanoic acid
Fmoc-2-Thienylalanine
MFCD00065676
SCHEMBL119606
PXBMQFMUHRNKTG-FQEVSTJZSA-N
Fmoc-beta-(2-thienyl)-Ala-OH
Fmoc-Ala(2-Thienyl)-OH
Fmoc-3-Ala(2-thienyl)-OH
HY-W011002
Fmoc-L-2-thienylalanine (Fmoc-L-2Thi-OH)
130309-35-2
AKOS015895572
CS-W011718
Fmoc-L-2-Thienylalanine
Fmoc-beta-(2-thienyl)-Ala-OH, >=98.0%
AC-9988
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-thiophen-2-ylpropanoic acid
Fmoc-L-3-(2-Thienyl)-L-alanine
J-505180
Fmoc-L-thienylalanine
Fmoc-3-(2-thienyl)-L-alanine
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(thiophen-2-yl)amino)propanoic acid
N-(9-Fluorenylmethoxycarbonyl)-2-thienyl-L-alanine
Fmoc-3-L-Ala(2-thienyl)-OH

MDL Number

MFCD00065676

FAQ

What regulatory guidelines apply to N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(2-thienyl)-L-alanine (CAS: 130309-35-2)?

This compound falls under various regulatory guidelines, including GHS (Global Harmonized System of Classification and Labelling of Chemicals) for hazardous substance identification, REACH (Registration, Evaluation, Authorization and Restriction of Chemicals) requirements for EU markets, and FDA (Food and Drug Administration) and EPA (Environmental Protection Agency) guidelines in the United States. Ensure compliance with local and international regulations for its use, storage, and disposal.

Are there alternatives to N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(2-thienyl)-L-alanine (CAS: 130309-35-2) in synthesis?

Alternatives to this compound include using related analogs such as N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine or other similar amino acids. Common alternative reagents in synthesis might include other fluorenylmethoxycarbonyl (Fmoc) protected amino acids or thienyl-containing compounds. These alternatives can be considered based on specific application requirements and availability.

What is the market or research trend for N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(2-thienyl)-L-alanine (CAS: 130309-35-2)?

Market and research trends indicate increasing interest in fluorenylmethoxycarbonyl (Fmoc) protected amino acids for their use in solid-phase peptide synthesis. Research is expanding into the development of novel thienyl-containing compounds for pharmaceutical and biotechnological applications. Demand is driven by their potential in drug discovery and synthesis of complex peptides.

How should waste containing N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(2-thienyl)-L-alanine (CAS: 130309-35-2) be handled?

Waste containing this compound should be collected in appropriate containers and properly labeled. For small quantities, it can be disposed of through incineration or other professional waste disposal methods. Implement necessary environmental protection precautions such as containment and proper handling to prevent environmental contamination. Always consult local regulations and guidelines for specific disposal requirements.