7-Methyl-6,8,9,16-tetrahydrobis[1,3]benzodioxolo[4,5-c:5',6'-g]azecin-15(7H)-one

Basic Information

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CAS Number

130-86-9

Molecular Formula

C20H19NO5

Molecular Weight

353.37 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Powder

Melting Point

201.0 to 205.0 deg-C

Boiling Point

486.8°C (rough estimate)

Flash Point

284.9 °C

Solubility

In water, 8.99 mg/L at 25 °C (est)

Refractive Index

1.5800 (estimate)

Vapor Pressure

6.36X10-10 mm Hg at 25 °C (est)

SMILES

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CN1CCC2=CC3=C(C=C2C(=O)CC4=C(C1)C5=C(C=C4)OCO5)OCO3

InChI

InChI=1S/C20H19NO5/c1-21-5-4-13-7-18-19(25-10-24-18)8-14(13)16(22)6-12-2-3-17-20(15(12)9-21)26-11-23-17/h2-3,7-8H,4-6,9-11H2,1H3

InChIKey

GPTFURBXHJWNHR-UHFFFAOYSA-N

LogP

2.5573000000000006

Topological Polar Surface Area

57.230000000000004 Å²

Hydrogen Bond Donor/Acceptor

0 / 6

Complexity

542

Safety Information

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GHS Hazard Pictograms

H301

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

Hazard Class

Class 6.1(b) Class 6.1(b)

Storage Conditions

2-8℃

Synonyms & References

English

SR-05000002290
AKOS000278163
AC-34931
Corydinine
EINECS 204-999-6
DTXCID7078773
4,6,7,14-Tetrahydro-5-methyl-bis[1,3]benzodioxolo[4,5-c-5,6-g]azecin-13(5H)-one
P2611
Corydalis C
C05189
CHEBI:16415
2D13E16B-20F9-4670-AD3E-02EE26A53C9C
15-methyl-7,9,19,21-tetraoxa-15-azapentacyclo[15.7.0.0^{4,12}.0^{6,10}.0^{18,22}]tetracosa-1(24),4(12),5,10,17,22-hexaen-3-one
NCGC00017389-01
7-Methyl-6,7,8,9-tetrahydro-[1,3]dioxolo[4',5':5,6]benzo[1,2-c][1,3]dioxolo[5',4':4,5]benzo[1,2-g]azecin-15(16H)-one
Macleyine
Biflorine
Hypercorine
4,6,7,14-Tetrahydro-5-methyl-bis(1,3)benzodioxolo(4,5-c-5',6'-g)azecin-13(5H)-one
Bis[1,3]benzodioxolo[4,5-c:5',6'-g]azecin-13(5H)-one, 4,6,7,14-tetrahydro-5-methyl-
7-methyl-2,3:9,10-bis[methylenebis(oxy)]-7,13a-secoberbin-13a-one
Oprea1_722246
Protopine, analytical standard
PROTOPINE [MI]
FT-0674127
NS00014909
15-methyl-7,9,19,21-tetraoxa-15-azapentacyclo[15.7.0.04,12.06,10.018,22]tetracosa-1(17),4,6(10),11,18(22),23-hexaen-3-one
4,6,7,14-Tetrahydro-5-methylbis[1,3]benzodioxolo[4,5-c:5',6'-g]azecin-13(5H)-one
protopine
Protopin
BDBM50286643

MDL Number

MFCD00022322

FAQ

What are the physical and chemical properties of 7-Methyl-6,8,9,16-tetrahydrobis[1,3]benzodioxolo[4,5-c:5',6'-g]azecin-15(7H)-one (CAS: 130-86-9)?

7-Methyl-6,8,9,16-tetrahydrobis[1,3]benzodioxolo[4,5-c:5',6'-g]azecin-15(7H)-one is a crystalline solid with a molecular weight of approximately 442.4 g/mol. It has moderate solubility in common organic solvents like methanol and ethanol, but is practically insoluble in water. This compound is relatively stable but can react with strong acids or bases, making it important to handle under controlled conditions.

How is 7-Methyl-6,8,9,16-tetrahydrobis[1,3]benzodioxolo[4,5-c:5',6'-g]azecin-15(7H)-one (CAS: 130-86-9) typically synthesized?

This compound is typically synthesized via multistep organic reactions, often involving the condensation of appropriate precursors followed by ring closure. The synthesis involves the use of catalysts such as p-toluenesulfonic acid and may require purification steps like recrystallization. It's important to ensure high selectivity and yield during the synthesis process.

What industries use 7-Methyl-6,8,9,16-tetrahydrobis[1,3]benzodioxolo[4,5-c:5',6'-g]azecin-15(7H)-one (CAS: 130-86-9)?

7-Methyl-6,8,9,16-tetrahydrobis[1,3]benzodioxolo[4,5-c:5',6'-g]azecin-15(7H)-one is used in the pharmaceutical and polymer industries. It can serve as a precursor in the development of new drugs and also as a monomer in the production of advanced polymers. Its unique structure makes it suitable for applications in sensors and semiconductors as well.

What precautions should be taken when handling 7-Methyl-6,8,9,16-tetrahydrobis[1,3]benzodioxolo[4,5-c:5',6'-g]azecin-15(7H)-one (CAS: 130-86-9)?

When handling this compound, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. Spills should be cleaned up immediately using suitable absorbents. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.