(15Z)-12-Hydroxysenecionan-11,16-dione

Basic Information

View in Editor

CAS Number

130-01-8

Molecular Formula

C18H25NO5

Molecular Weight

335.4 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Powder

Melting Point

244 ºC

Boiling Point

472.03°C (rough estimate)

Refractive Index

1.5100 (estimate)

Vapor Pressure

1.8X10-12 mm Hg @ 25 °C /Estimated/

Specific Rotation

D25 -55.1° (c = 0.034 in chloroform)

SMILES

View in Editor

CC=C1CC(C(C(=O)OCC2=CCN3C2C(CC3)OC1=O)(C)O)C

InChI

InChI=1S/C18H25NO5/c1-4-12-9-11(2)18(3,22)17(21)23-10-13-5-7-19-8-6-14(15(13)19)24-16(12)20/h4-5,11,14-15,22H,6-10H2,1-3H3/b12-4-/t11-,14-,15-,18-/m1/s1

InChIKey

HKODIGSRFALUTA-JTLQZVBZSA-N

LogP

1.1928

Topological Polar Surface Area

76.07 Å²

Hydrogen Bond Donor/Acceptor

1 / 6

Complexity

611

Safety Information

View Safety Information

Hazard Class

Class 6.1(a) Class 6.1(a)

Storage Conditions

2-8℃

Toxicity

LD50 i.v. in mice: 64.12 ±2.24 mg/kg (Harris)

Synonyms & References

English

UNII-BO6N1U5YG6
NSC89935
CHEBI:9107
BDBM50480301
C06176
1ST40300
Senecionine, analytical standard
Q2083871
SENECIONINE
BRN 0934445
A905119
WLN: T55-12-1A Q EN IOVY OVO BUTJ KU2 M NQ N
AC-34604
Senecionine, >=95.0% (GC)
HSDB 3535
DTXCID501474669
Senecionan-11,16-dione, 12-hydroxy-
[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione,3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-5,6-dimethyl-,(3Z,5R,6R,14aR,14bR)-
Aureine
12-Hydroxysenecionan-11,16-dione
NSC 89935
(-)-SENECIONINE
(5R,6R,9a1R,14aR,Z)-3-ethylidene-6-hydroxy-5,6-dimethyl-3,4,5,6,9,9a1,11,13,14,14a-decahydro-[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione
NCGC00163621-01
AS-79841
Senecionin
130-01-8
CHEMBL362153
AI3-51771
(1,6)Dioxacyclododecino(2,3,4-gh)pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-5,6-dimethyl-, (3Z,5R,6R,14aR,14bR)-
CCG-208634

MDL Number

MFCD00221720

FAQ

What is (15Z)-12-Hydroxysenecionan-11,16-dione (CAS: 130-01-8)?

(15Z)-12-Hydroxysenecionan-11,16-dione is a sesquiterpene lactone with a CAS number of 130-01-8. It is characterized by a 15Z double bond, a 12-hydroxyl group, and a 11,16-dione structure. This compound is primarily found in certain plant species and has been studied for its potential biological activities.

What are the main uses of (15Z)-12-Hydroxysenecionan-11,16-dione (CAS: 130-01-8)?

(15Z)-12-Hydroxysenecionan-11,16-dione is used in research for its potential biological activities, including anti-inflammatory, antifungal, and anticancer properties. It may also be used in the development of pharmaceuticals and as a natural product in cosmetics and food additives.

Is (15Z)-12-Hydroxysenecionan-11,16-dione (CAS: 130-01-8) safe?

(15Z)-12-Hydroxysenecionan-11,16-dione is generally considered safe for use in research and pharmaceutical applications when handled properly. However, it should be used with caution due to its potential toxicity. Protective measures such as gloves and lab coats are recommended to prevent skin contact and inhalation. Ensure proper ventilation and avoid contact with eyes and skin.

How should (15Z)-12-Hydroxysenecionan-11,16-dione (CAS: 130-01-8) be stored?

(15Z)-12-Hydroxysenecionan-11,16-dione should be stored in a cool, dry place away from direct sunlight and moisture. It is best to keep it in a tightly sealed container to maintain purity and stability. Avoid temperatures above 30°C, and store in a shaded area if possible. Proper storage is essential to preserve its biological activity and prevent degradation.