5-Bromo-6-methoxypyridin-3-ol

Basic Information

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CAS Number

1299312-97-2

Molecular Formula

C6H6BrNO2

Molecular Weight

204.02 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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COC1=C(C=C(C=N1)O)Br

InChI

InChI=1S/C6H6BrNO2/c1-10-6-5(7)2-4(9)3-8-6/h2-3,9H,1H3

InChIKey

GPLHBPPGBOMBRH-UHFFFAOYSA-N

LogP

1.5582999999999998

Topological Polar Surface Area

42.35 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

112

Synonyms & References

English

5-Bromo-6-methoxypyridin-3-ol
C72194
A888806
1299312-97-2
MFCD26383571
SCHEMBL12165565
DTXSID80738137
AS-60466
AKOS022172245
DB-368573
ZBC31297

MDL Number

MFCD26383571

FAQ

What are the physical and chemical properties of 5-Bromo-6-methoxypyridin-3-ol (CAS: 1299312-97-2)?

5-Bromo-6-methoxypyridin-3-ol is a crystalline solid with a molecular weight of approximately 236.04 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetonitrile. The compound is slightly reactive and can undergo substitution reactions, particularly under basic conditions.

How is 5-Bromo-6-methoxypyridin-3-ol (CAS: 1299312-97-2) typically synthesized?

5-Bromo-6-methoxypyridin-3-ol is synthesized by bromination of 6-methoxypyridin-3-ol using N-bromosuccinimide (NBS) in an appropriate solvent like acetone or acetonitrile. The reaction is typically carried out under light to promote the bromination process, resulting in a good yield and high selectivity.

What industries use 5-Bromo-6-methoxypyridin-3-ol (CAS: 1299312-97-2)?

5-Bromo-6-methoxypyridin-3-ol is used in the pharmaceutical industry for the development of certain drugs. It may also find applications in the synthesis of materials for sensors and semiconductors due to its functional groups that can participate in various reactions.

What precautions should be taken when handling 5-Bromo-6-methoxypyridin-3-ol (CAS: 1299312-97-2)?

When handling 5-Bromo-6-methoxypyridin-3-ol, it is important to wear appropriate personal protective equipment (PPE) such as gloves and goggles. The compound should be handled in a fume hood to minimize inhalation risks. In case of a spill, it should be carefully cleaned up with appropriate absorbent materials, and the area should be well-ventilated. Always consult the Safety Data Sheet (SDS) for detailed handling instructions.