Loteprednol | CAS No. 129260-79-3

Loteprednol

Basic Information

View in Editor

CAS Number

129260-79-3

Molecular Formula

C21H27ClO5

Molecular Weight

394.9 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Basic Physical Properties

SMILES

View in Editor

CC12CC(C3C(C1CCC2(C(=O)OCCl)O)CCC4=CC(=O)C=CC34C)O

InChI

InChI=1S/C21H27ClO5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,18(25)27-11-22)20(15,2)10-16(24)17(14)19/h5,7,9,14-17,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,17+,19-,20-,21-/m0/s1

InChIKey

YPZVAYHNBBHPTO-MXRBDKCISA-N

LogP

2.7357000000000014

Topological Polar Surface Area

83.83 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

745

Synonyms & References

English

EN300-19634418
DTXSID10156128
LOTEPREDNOL [INN]
DTXCID0078619
loteprednol
DB00873
CHEBI:50848
S01BA14
Loteprednolum
chloromethyl (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylate
UNII-Z8CBU6KR16
Loteprednol [INN:BAN]
D08147
LOTEPREDNOL [VANDF]
AKOS015840095
Z8CBU6KR16
129260-79-3
SCHEMBL3826
chloromethyl (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-14-carboxylate
chloromethyl 11beta,17alpha-dihydroxy-3-oxoandrosta-1,4-diene-17beta-carboxylate
chloromethyl (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-17-carboxylate
Androsta-1,4-diene-17-carboxylic acid, 11,17-dihydroxy-3-oxo-, chloromethyl ester, (11beta,17alpha)-
Loteprednol (INN)
chloromethyl (1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene-1-carboxylate
LOTEPREDNOL [WHO-DD]
Loteprednol
17a-Hydroxy-11b-hydroxy-3-oxoandrosta-1,4-diene-17-carboxylic acid chloromethyl ester
SureCN3826
Loteprednol-D5
Loteprednol base

MDL Number

MFCD09837665

FAQ

What is Loteprednol (CAS: 129260-79-3)?

Loteprednol is a corticosteroid used in ophthalmic medications. It has the chemical formula C24H33FO7 and is known for its anti-inflammatory and immunosuppressive properties.

What are the main uses of Loteprednol (CAS: 129260-79-3)?

Loteprednol is primarily used in the treatment of ocular inflammation, such as keratitis and uveitis. It is formulated into eye drops for topical application.

Is Loteprednol (CAS: 129260-79-3) safe?

Loteprednol is generally considered safe when used as directed. However, it can cause side effects such as cataracts and increased intraocular pressure. It is important to follow medical advice and use it only as prescribed.

How should Loteprednol (CAS: 129260-79-3) be stored?

Loteprednol should be stored at room temperature (15-30°C or 59-86°F) and protected from direct sunlight. It should be kept in a tightly closed container to prevent contamination and preserve its efficacy.