Hexasodium 8,8'-{carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]}di(1,3,5-naphthalenetrisulfonate)

Basic Information

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CAS Number

129-46-4

Molecular Formula

C51H34N6Na6O23S6

Molecular Weight

1429.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

Not available

Boiling Point

Not available

Density

Not available

Flash Point

Not available

Solubility

H2O: >10mg/mL

Vapor Pressure

Not available

SMILES

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CC1=C(C=C(C=C1)C(=O)NC2=C3C(=CC(=CC3=C(C=C2)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])NC(=O)C4=CC(=CC=C4)NC(=O)NC5=CC=CC(=C5)C(=O)NC6=C(C=CC(=C6)C(=O)NC7=C8C(=CC(=CC8=C(C=C7)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])C.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]

InChI

InChI=1S/C51H40N6O23S6.6Na/c1-25-9-11-29(49(60)54-37-13-15-41(83(69,70)71)35-21-33(81(63,64)65)23-43(45(35)37)85(75,76)77)19-39(25)56-47(58)27-5-3-7-31(17-27)52-51(62)53-32-8-4-6-28(18-32)48(59)57-40-20-30(12-10-26(40)2)50(61)55-38-14-16-42(84(72,73)74)36-22-34(82(66,67)68)24-44(46(36)38)86(78,79)80;;;;;;/h3-24H,1-2H3,(H,54,60)(H,55,61)(H,56,58)(H,57,59)(H2,52,53,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80);;;;;;/q;6*+1/p-6

InChIKey

VAPNKLKDKUDFHK-UHFFFAOYSA-H

LogP

11.61040

Complexity

2940

Safety Information

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Sensitiveness

对热敏感

Toxicity

LD50 in mice (mg/kg): ~620 i.v. (Hawking)

Synonyms & References

English

BAY-205
suramin hexasodium salt
HMS3412D13
MFCD00210217
Naphuride sodium
AS-81747
8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt
Lopac-S-149
89521262IH
SURAMIN SODIUM [MI]
CHEBI:9364
NCGC00261867-01
Naphuride
309 F
Suramine sodique
1,3,5-NAPHTHALENETRISULFONIC ACID, 8,8'-(CARBONYLBIS(IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO))BIS-, SODIUM SALT (1:6)
8,8'-(UREYLENEBIS(M-PHENYLENE CARBONYLIMINO(4-METHYL-M-PHENYLENE)CARBONYLIMINO))DI(1,3,5-NAPHTHALENETRISULFONIC ACID) HEXASODIUM SALT
UNII-89521262IH
Bayer 205 (TN)
sodium 8,8'-((3,3'-((3,3'-(carbonylbis(azanediyl))bis(benzoyl))bis(azanediyl))bis(4-methylbenzoyl))bis(azanediyl))bis(naphthalene-1,3,5-trisulfonate)
SK 24728
CHEMBL413376
Suramin Hexasodium [USAN]
Suramin (sodium salt)
NS00079136
NF-060
Suramine sodium salt
S-149
LP01182
SURAMIN SODIUM [WHO-IP]
HMS2092P13

MDL Number

MFCD00210217

FAQ

What are the physical and chemical properties of Hexasodium 8,8'-{carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]}di(1,3,5-naphthalenetrisulfonate) (CAS: 129-46-4)?

This compound has a white crystalline form with a high molecular weight. It is poorly soluble in water but soluble in polar aprotic solvents. Chemically, it is highly reactive towards nucleophiles and electron donors. It decomposes at high temperatures. Its solubility and reactivity make it interesting for various applications.

How is Hexasodium 8,8'-{carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]}di(1,3,5-naphthalenetrisulfonate) (CAS: 129-46-4) typically synthesized?

The compound is synthesized by a multistep process involving organic synthesis methods such as coupling reactions and sulfonation. Commonly, this involves the use of sodium naphthalene sulfonate, 4-methylbenzene, and various transition metal catalysts. The yield and selectivity of the reaction can be controlled by optimizing reaction conditions.

What industries use Hexasodium 8,8'-{carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]}di(1,3,5-naphthalenetrisulfonate) (CAS: 129-46-4)?

This compound is used in the pharmaceutical industry for its unique reactivity, in the polymer industry for its ability to enhance polymer properties, and in the semiconductor industry for its role in sensor applications. It also finds use in analytical chemistry and as a reagent in various chemical processes.

What precautions should be taken when handling Hexasodium 8,8'-{carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]}di(1,3,5-naphthalenetrisulfonate) (CAS: 129-46-4)?

Handle with gloves and in a fume hood due to its reactivity. Store in a cool, dry place away from direct sunlight. In case of spill, handle according to the Safety Data Sheet (SDS) and dispose of properly. Always wear appropriate personal protective equipment (PPE) during handling and laboratory operations.