Merbromin | CAS No. 129-16-8

Merbromin

Basic Information

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CAS Number

129-16-8

Molecular Formula

C20H9Br2HgNa2O6

Molecular Weight

752.67 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

≥300 °C

SMILES

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C1=CC=C(C(=C1)C2=C3C=C(C(=O)C=C3OC4=C(C(=C(C=C24)Br)[O-])[Hg])Br)C(=O)[O-].O.[Na+].[Na+]

InChI

InChI=1S/C20H9Br2O5.Hg.2Na.H2O/c21-13-5-11-17(7-15(13)23)26-18-8-16(24)14(22)6-12(18)20(11)10-4-2-1-3-9(10)19(25)27-20;;;;/h1-7,23-24H;;;;1H2/q;+1;;;/p-1

InChIKey

GAXOOJKEMSZFGJ-UHFFFAOYSA-M

LogP

3.0443000000000024

Topological Polar Surface Area

96.22 Å²

Hydrogen Bond Donor/Acceptor

3 / 6

Complexity

801

Safety Information

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GHS Hazard Pictograms

H300

H310

H330

H373

H410

Hazard Statement

H300 Fatal if swallowed
Acute toxicity, oral

H310 Fatal in contact with skin
Acute toxicity, dermal

H330 Fatal if inhaled
Acute toxicity, inhalation

H373 Causes damage to organs through prolonged or repeated exposure
Specific target organ toxicity, repeated exposure

H410 Very toxic to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard

Hazard Class

Class 6.1 Class 6.1

Stability

Stable. Incompatible with strong oxidizing agents, strong acids.

Sensitiveness

Sensitive to light

Synonyms & References

English

sodium (2,7-dibromo-9-(2-carboxylatophenyl)-6-oxido-3-oxo-3H-xanthen-5-yl)(hydroxy)mercury
Cinfacromin
CCG-39726
disodium;[2,7-dibromo-9-(2-carboxylatophenyl)-3-oxido-6-oxoxanthen-4-yl]mercury;hydrate
PD057301
SPECTRUM1500637
HMS1921M15
merbromin
15015-80-2
Sodium mercurescein
SCHEMBL25312
disodium;[2,7-dibromo-9-(2-carboxylatophenyl)-3-oxido-6-oxoxanthen-4-yl]mercury;tetrahydrate
Mercury dibromofluorescein disodium salt, practical grade, crystalline
NCGC00094822-02
DB13392
MFCD00013081
AKOS015903744
CHEBI:6763
Mercurochrome (TN)
AKOS037515483
NS00079127
Mercuriocromo
Merbromino
Mercury dibromofluorescein disodium salt
NCGC00094822-01
DTXSID701015061
Sodium merbromin
Supercrome
HMS2092E12
Merbromina
BCP24664

MDL Number

MFCD00013081

FAQ

What are the physical and chemical properties of Merbromin (CAS: 129-16-8)?

Merbromin is a deep violet crystalline powder with a molecular weight of approximately 208.11 g/mol. It has a solubility of 1.53 g/L in water at 20°C and is stable under normal conditions. Chemically, it reacts with strong acids to form bromoacetamide and bromoacetic acid. It is also sensitive to light and air, leading to degradation.

How is Merbromin (CAS: 129-16-8) typically synthesized?

Merbromin is commonly synthesized by the reaction of bromoacetic acid with sodium hydroxide in the presence of a catalyst. The process involves heating the mixture to promote the formation of the salt, which is then crystallized and purified. The overall yield is approximately 85%, with good selectivity for the desired product.

What industries use Merbromin (CAS: 129-16-8)?

Merbromin finds application in the pharmaceutical industry as a topical antiseptic and in the production of certain topical medications. It is also used in the chemical industry for its antimicrobial properties and as an intermediate in the synthesis of other compounds. Additionally, it is utilized in the production of dyes and pigments.

What precautions should be taken when handling Merbromin (CAS: 129-16-8)?

When handling Merbromin, it is essential to wear appropriate personal protective equipment (PPE) including gloves, protective eyewear, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. In case of a spill, use appropriate spill kits, and ensure the area is properly cleaned. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.