2-((3-Fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid | CAS No. 1289942-66-0
2-((3-Fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid
Basic Information
CAS Number
1289942-66-0
Molecular Formula
C12H15FN2O3
Molecular Weight
254.26 g/mol
AD
Basic Physical Properties
Boiling Point
455 ºC
Flash Point
229 ºC
Safety Information
View Safety InformationHazard Statement
H302
Harmful if swallowed
Acute toxicity, oral
Acute toxicity, oral
H315
Causes skin irritation
Skin corrosion/irritation
Skin corrosion/irritation
H319
Causes serious eye irritation
Serious eye damage/eye irritation
Serious eye damage/eye irritation
H335
May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Synonyms & References
English
- 2-[3-fluoro-4-(methylcarbamoyl)anilino]-2-methyl-propanoic Acid
- 4SC-101
- CHEMBL197194
- 2-(3-fluoro-4-(methylcarbamoyl)phenylamino)-2-methylpropanoic acid
- UNII-8Y1PJ3VG81
- KB-81442
- Vidofludimus [INN]
- 2-(3-fluoro-4-methylcarbamoyl-phenylamino)-2-methyl-propionic acid
- SureCN247888
- 2-((3-fluoro-3'-methoxy-[1,1'-biphenyl]-4-yl)carbamoyl)cyclopent-1-enecarboxylic acid
- vidofludimus
- 2-(3-Fluoro-3'-methoxy-biphenyl-4-ylcarbamoyl)-cyclopent-1-ene-carboxylic acid
- 2-((3-Fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid
- 2-((3-Fluoro-4-(methylcarbamoyl)phenyl)-amino)-2-methylpropanoic acid
- Alanine, N-[3-fluoro-4-[(methylamino)carbonyl]phenyl]-2-methyl-
- Alanine, N-[3-fluoro-4-[(methylamino)carbonyl]phenyl]-2-methyl19
- N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine
- N-[3-fluoro-4-[(methylamino)carbonyl]phenyl]-2-methyl-Alanine
- N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine(for Enzalutamide)
- 2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid
- PD196177
- 1289942-66-0
- 2-{[3-FLUORO-4-(METHYLCARBAMOYL)PHENYL]AMINO}-2-METHYLPROPANOIC ACID
- Enzalutamide ITS-2
- MFCD22581651
- N-[3-Fluoro-4-[(MethylaMino)carbonyl]phenyl]-2-Methylalanine
- SY116162
- 2-((3-Fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoicacid
- AMY16509
- 2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methyl propanoic acid
- 2-(3-fluoro-4-(methylcarbamoyl)phenylamino)-2-methylpropanoic acid;2-[[3-Fluoro-4-(methylcarbamoyl)phenyl]amino]-2-methylpropanoic Acid
MDL Number
MFCD22581651
FAQ
What are the physical and chemical properties of 2-((3-Fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid (CAS: 1289942-66-0)?
2-((3-Fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid is a crystalline solid with a molecular weight of approximately 329.29 g/mol. It has a low solubility in water but is more soluble in organic solvents like methanol and ethanol. Chemically, it is relatively stable but can react with strong acids or bases under certain conditions. This compound is typically used in pharmaceutical applications due to its structural complexity and potential medicinal value.
How is 2-((3-Fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid (CAS: 1289942-66-0) typically synthesized?
2-((3-Fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid is synthesized through a multi-step process involving the coupling of a fluoroaniline derivative with a methyl carbamate followed by condensation with an amino acid. The reaction is catalyzed by a transition metal such as palladium under conditions of microwave heating or other suitable methodologies. The overall yield is around 60-70%, with good selectivity towards the desired product.
What industries use 2-((3-Fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid (CAS: 1289942-66-0)?
2-((3-Fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid finds applications in the pharmaceutical industry, particularly in the development of new drugs. Its complex structure and potential therapeutic value make it a valuable intermediate in the synthesis of novel medications. It is also explored in the field of polymer chemistry for its potential use in the formulation of advanced materials with specific properties.
What precautions should be taken when handling 2-((3-Fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid (CAS: 1289942-66-0)?
Handling 2-((3-Fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid requires appropriate personal protective equipment (PPE), including gloves and goggles. This compound should be used in a well-ventilated area or under a fume hood to avoid inhalation. Spills should be cleaned up promptly using appropriate absorbent materials. The Material Safety Data Sheet (MSDS) should be consulted for detailed handling and disposal information to ensure safe laboratory practices.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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