N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(2-methyl-2-propanyl)-D-serine

Basic Information

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CAS Number

128107-47-1

Molecular Formula

C22H25NO5

Molecular Weight

383.44 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

131℃

Boiling Point

578.6°C at 760 mmHg

SMILES

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CC(C)(C)OCC(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

InChI

InChI=1S/C22H25NO5/c1-22(2,3)28-13-19(20(24)25)23-21(26)27-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,23,26)(H,24,25)/t19-/m1/s1

InChIKey

REITVGIIZHFVGU-LJQANCHMSA-N

LogP

3.7934000000000028

Topological Polar Surface Area

84.86 Å²

Hydrogen Bond Donor/Acceptor

2 / 6

Complexity

536

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Fmoc-O-tert.butyl-D-serine
9-Fluorenylmethoxycarbonyl-o-t-butyl-d-serine;Fmoc-D-Ser(tBu)-OH
(2R)-3-(tert-butoxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
A26748
O-tert-Butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-serine
K5W4U4PS9D
(2R)-3-(tert-butoxy)-2-[(fluoren-9-ylmethoxy)carbonylamino]propanoic acid
(2R)-3-(tert-Butoxy)-2-([[(9H-fluoren-9-yl)methoxy]carbonyl]amino)propanoic acid
128107-47-1
AM82226
EN300-204844
Fmoc-D-Ser(Bu-t)-OH
M03384
J-300240
MFCD00077071
AKOS030228152
CS-W008156
AC-30046
O-tert-Butyl-N-Fmoc-L-serine
DS-1073
N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyl)-D-serine
HY-W008156
(R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-tert-butoxypropanoic acid
Fmoc-O-tert-butyl-D-serine
Fmoc-D-Ser(tBu)-OH
N-Fmoc-O-tert-butyl-D-serine, 98% (Fmoc-D-Ser(tBu)-OH)
(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[(2-methylpropan-2-yl)oxy]propanoic acid
B3168
SCHEMBL119565
Fmoc-D-Ser(tBu)-OH, >=98.0% (TLC)
AKOS015837434

MDL Number

MFCD00077071

FAQ

What regulatory guidelines apply to N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(2-methyl-2-propanyl)-D-serine (CAS: 128107-47-1)?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(2-methyl-2-propanyl)-D-serine (CAS: 128107-47-1) is subject to various regulatory guidelines. It must comply with GHS classification for hazardous substances, REACH regulations for European market, and FDA/EPA requirements for pharmaceutical and chemical applications, respectively. Manufacturers and handlers should ensure compliance with local and international safety and environmental regulations.

Are there alternatives to N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(2-methyl-2-propanyl)-D-serine in synthesis (CAS: 128107-47-1)?

Yes, there are alternatives to N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(2-methyl-2-propanyl)-D-serine in synthesis. Common alternatives include other serine analogs, such as 2-methyl-2-propanol derivatives or fluorenylmethoxycarbonyl protected serines. These alternatives can offer similar functionalities or improved synthetic pathways depending on the specific application.

What is the market or research trend for N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(2-methyl-2-propanyl)-D-serine (CAS: 128107-47-1)?

The market for N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(2-methyl-2-propanyl)-D-serine (CAS: 128107-47-1) is experiencing growth driven by its use in pharmaceuticals, particularly in drug synthesis. Research trends are focusing on its use as a protective group in peptide synthesis and as a precursor in medicinal chemistry. Market trends suggest increasing demand in specialty chemical and pharmaceutical sectors.

How should waste containing N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(2-methyl-2-propanyl)-D-serine (CAS: 128107-47-1) be handled?

Waste containing N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(2-methyl-2-propanyl)-D-serine (CAS: 128107-47-1) should be collected and disposed of according to local waste management regulations. Typically, this involves neutralization and incineration, or professional waste disposal services. Environmental protection precautions include ensuring containment to prevent spillage and proper labeling of waste containers to facilitate safe handling and disposal.