1-Chloro-2,5-pyrrolidinedione

Basic Information

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CAS Number

128-09-6

Molecular Formula

C4H4ClNO2

Molecular Weight

133.53 g/mol

Basic Physical Properties

Melting Point

148-150 °C

Boiling Point

200.5ºC at 760 mmHg

Water Solubility

Soluble in water, alcohol, benzene, acetone and acetic acid. Slightly soluble in ether, chloroform, carbon tetrachloride and petroleum ether.

Flash Point

75.1ºC

Solubility

14g/l

Refractive Index

1.4378 (estimate)

SMILES

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ClN1C(=O)CCC1=O

InChI

InChI=1S/C4H4ClNO2/c5-6-3(7)1-2-4(6)8/h1-2H2

InChIKey

JRNVZBWKYDBUCA-UHFFFAOYSA-N

LogP

0.2892

Topological Polar Surface Area

37.38 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

129

Safety Information

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GHS Hazard Pictograms

H302

H314

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Sensitiveness

Moisture Sensitive

Toxicity

MLD orally in rats: 2.7 g/kg (Stohlman, Smith)

Synonyms & References

English

1-Chloropyrrolidine-2,5-dione
1-Chloro-2,5-piperidinedione
1-chloro-5-pyrrolidinedione
5-Pyrrolidinedione,1-chloro-2
imide,n-chloro-succinicaci
n-chloro-succinimid
Pyrrolidinedione, 1-chloro-
Succinic N-chloroimide
N-Chlorosuccinimide
N-Chlorobutanimide
NCS
1-Chloro-2,5-pyrrolidinedione
Chlorosuccinimide
Succinchlorimide
Succinochlorimide
CHLOROSUCCINAMIDE
N-Chlor-succinimid
N-Chlorosuccinimie
NCS;N-chlorosuccinimide;N-chlorobutanimide
2,5-Pyrrolidinedione, 1-chloro-
Succinimide, N-chloro-
Caswell No. 807
N-chloro-succinimide
Succinic acid, imide, N-chloro-
EPA Pesticide Chemical Code 077301
0FWP306H7X
1-Chloro-2,5-pyrrolidine-dione
JRNVZBWKYDBUCA-UHFFFAOYSA-N
N-C
1-chloropyrrolidine-2,5-dione

MDL Number

MFCD00005511

Customs Code

2933990090

FAQ

What is 1-Chloro-2,5-pyrrolidinedione (CAS: 128-09-6)?

1-Chloro-2,5-pyrrolidinedione (CAS: 128-09-6) is a cyclic organic compound containing a pyrrolidinedione ring with a chlorine atom at the 1-position. It is a colorless liquid with a pungent odor and exhibits moderate solubility in water. This compound is known for its reactivity and is commonly used in organic synthesis as an intermediate.

What are the main uses of 1-Chloro-2,5-pyrrolidinedione (CAS: 128-09-6)?

1-Chloro-2,5-pyrrolidinedione (CAS: 128-09-6) is primarily used in pharmaceutical research for the synthesis of various drugs and as a building block in the production of agrochemicals. It also finds applications in the manufacture of specialty chemicals and as a reagent in organic chemistry for functional group transformations.

Is 1-Chloro-2,5-pyrrolidinedione (CAS: 128-09-6) safe?

1-Chloro-2,5-pyrrolidinedione (CAS: 128-09-6) is considered hazardous and requires careful handling. It can cause skin and eye irritation, and inhalation may lead to respiratory issues. Safety measures include using personal protective equipment (PPE), ensuring proper ventilation, and following standard chemical safety protocols to minimize exposure.

How should 1-Chloro-2,5-pyrrolidinedione (CAS: 128-09-6) be stored?

1-Chloro-2,5-pyrrolidinedione (CAS: 128-09-6) should be stored in a cool, dry, and well-ventilated area, away from light and incompatible substances. It is best kept in a sealed container at a temperature below 25°C and in a humidity-controlled environment to maintain stability and prevent degradation.