Ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate | CAS No. 1276110-06-5
Ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate
Basic Information
CAS Number
1276110-06-5
Molecular Formula
C21H18N4O4S
Molecular Weight
422.47 g/mol
AD
Chemical Classification
Basic Physical Properties
Solubility
Insuluble (3.6E-3 g/L) (25 ºC),
Safety Information
View Safety InformationHazard Statement
H302
Harmful if swallowed
Acute toxicity, oral
Acute toxicity, oral
H315
Causes skin irritation
Skin corrosion/irritation
Skin corrosion/irritation
H319
Causes serious eye irritation
Serious eye damage/eye irritation
Serious eye damage/eye irritation
H335
May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Synonyms & References
English
- HS-173
- 6-?[5-?[(phenylsulfonyl)?amino]?-?3-?pyridinyl]Imidazo[1,?2-?a]?pyridine-?3-?carboxylic acid ethyl ester
- ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]-pyridine-3-carboxylate
- HS173
- Ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate
- HS 173
- GTPL8243
- AOB6845
- HMS3653I16
- BCP09225
- BDBM50341493
- s7356
- 2465AH
- SB19242
- AK474032
- BC600371
- SW219873-1
- A13021
- ethyl 6-[5-(benzenesulfonamido)pyridin-3-yl]imidazo[1,2-a]pyridine-3-carboxylate
- Ethyl 6-(5-(Phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]
- NCGC00386329-02
- CS-6015
- NCGC00386329-06
- AC-35309
- HY-15868
- EN300-202619
- CCG-268913
- Ethyl 6-(5-(Phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]-pyridine-3-carboxylate
- J-690118
- ethyl 6-[5-(benzenesulfonamido)-3-pyridyl]imidazo[1,2-a]pyridine-3-carboxylate
- MFCD28023584
MDL Number
MFCD28023584
FAQ
What are the physical and chemical properties of Ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate (CAS: 1276110-06-5)?
Ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate (CAS: 1276110-06-5) is a crystalline compound with a molecular weight of approximately 519.5 g/mol. It has limited water solubility and is soluble in organic solvents like DMSO. This compound exhibits moderate reactivity, particularly towards nucleophiles, and is stable under normal laboratory conditions.
How is Ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate (CAS: 1276110-06-5) typically synthesized?
Ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate (CAS: 1276110-06-5) is typically synthesized through multi-step reactions involving the coupling of an imidazo[1,2-a]pyridine derivative with a phenylsulfonamido pyridine, using appropriate bases and solvents. The reaction yield is generally around 75-85% and the process requires careful control of reaction conditions to achieve high selectivity.
What industries use Ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate (CAS: 1276110-06-5)?
Ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate (CAS: 1276110-06-5) is used in the pharmaceutical industry for its potential as an intermediate in drug discovery and development. It may also find applications in the polymer industry for specific functional properties and in chemical sensing for its ability to respond to certain stimuli.
What precautions should be taken when handling Ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate (CAS: 1276110-06-5)?
When handling Ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate (CAS: 1276110-06-5), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood. Spills should be cleaned up using appropriate absorbent materials, and the compound should be stored in a cool, dry place away from direct sunlight and heat sources. Refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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