(3R)-3-Piperidinamine

Basic Information

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CAS Number

127294-73-9

Molecular Formula

C5H12N2

Molecular Weight

100.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

157.9°C at 760 mmHg

SMILES

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C1CC(CNC1)N

InChI

InChI=1S/C5H12N2/c6-5-2-1-3-7-4-5/h5,7H,1-4,6H2/t5-/m1/s1

InChIKey

PEUGKEHLRUVPAN-RXMQYKEDSA-N

LogP

-0.30289999999999995

Topological Polar Surface Area

38.05 Å²

Hydrogen Bond Donor/Acceptor

3 / 2

Complexity

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(3R)-3-piperidinamine
EN300-142334
(3R)-piperidin-3-amine
SCHEMBL1490050
(R)-piperidin-3-amine
(R)-3-AMINOPIPERIDINE
MFCD03093369
127294-73-9
A805678
(R)-piperidine-3-amine
CS-W009139
DS-12300
J-502214
C72133
AKOS006238591
r-3-aminopiperidine
PEUGKEHLRUVPAN-RXMQYKEDSA-N
AKOS016016504
3-(r)-aminopiperidine
DTXSID00349860
AMY258
(3R)-piperidin-3-amine;(R)-Piperidin-3-amine
3-Piperidinamine, (3R)-
(R)-Piperidin-3-amine
(R)-piperidin-3-ylamine.2HCl
3-amino-dihydropyridine
3-aminopiperidine
m-aminopiperidine
3-Piperidinamine,(R)-
(3R)-3-Piperidinamine
3-PiperidinaMine, (3R)-

MDL Number

MFCD03093369

Customs Code

2933399090

FAQ

What are the physical and chemical properties of (3R)-3-Piperidinamine (CAS: 127294-73-9)?

(3R)-3-Piperidinamine is a white crystalline solid with a molecular weight of approximately 107.16 g/mol. It has a pKa of about 10.5 and is slightly soluble in water. Chemically, it is an amine and displays basic properties. It is reactive towards acidic compounds and can undergo nucleophilic substitution reactions.

How is (3R)-3-Piperidinamine (CAS: 127294-73-9) typically synthesized?

(3R)-3-Piperidinamine can be synthesized via the reduction of (3R)-3-piperidone. Common methods include catalytic hydrogenation with a palladium catalyst or the use of sodium borohydride as a reducing agent. The yield is typically around 75-90% with good selectivity.

What industries use (3R)-3-Piperidinamine (CAS: 127294-73-9)?

(3R)-3-Piperidinamine is widely used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It is also utilized in the production of certain polymers and as a ligand in catalyst systems. Additionally, it has applications in the chemical and material sciences, including sensor technology and semiconductor manufacturing.

What precautions should be taken when handling (3R)-3-Piperidinamine (CAS: 127294-73-9)?

When handling (3R)-3-Piperidinamine, appropriate personal protective equipment (PPE) should be worn, including gloves, goggles, and a laboratory coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbent materials, and the area should be thoroughly rinsed with water. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.