N,N-Dimethylacetamide | CAS No. 127-19-5

N,N-Dimethylacetamide

Basic Information

CAS Number

127-19-5

Molecular Formula

C4H9NO

Molecular Weight

87.12 g/mol

AD

Basic Physical Properties

Melting Point

−20 °C

Boiling Point

164.5-166 °C

Water Solubility

miscible

Solubility

>1000g/l soluble

Refractive Index

n20/D 1.437(lit.)

Vapor Pressure

2 mmHg ( 25 °C)<br />4 mmHg ( 38 °C)

CC(=O)N(C)C

InChI

InChI=1S/C4H9NO/c1-4(6)5(2)3/h1-3H3

InChIKey

FXHOOIRPVKKKFG-UHFFFAOYSA-N

LogP

0.09450000000000003

Topological Polar Surface Area

20.310000000000002 Ų

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

58.6

Safety Information

View Safety Information

GHS Hazard Pictograms

H312H312
H332H332

Hazard Statement

H312 Harmful in contact with skin
Acute toxicity, dermal
H332 Harmful if inhaled
Acute toxicity, inhalation

Stability

Stable. Combustible. Incompatible with strong oxidizing agents.

Sensitiveness

prone to moisture absorption

Explosive Limit

1.7-11.5%(V)

Toxicity

LD50 orally in rats: 5.4 ml/kg (Bartsch)

Synonyms & References

English

  • N,N-Dimethylacetamide
  • 1,2-DICHLOROPROPANE
  • PROPYLENE CHLORIDE
  • PROPYLENE DICHLORIDE
  • Acetyldimeethylamine
  • CBC 510337
  • CH3CON(CH3)2
  • dimethylacetamid
  • dimethylacetoneamide
  • Dimethylamid kyseliny octove
  • Dimethylamide acetate
  • Hallucinogen
  • n,n-dimethyl-acetamid
  • NSC 3138
  • SK 7176
  • Acetic acid dimethylacetamide
  • N-N-Dimethylacetamide
  • DMAC
  • N,N-Dimethylacetamide Solution
  • N,N-DIMETHYLACETAMIDE, ANHYDROUS
  • N,N-Dimethylacetamide, Super Dehydrated
  • Dimethylacetamide
  • Acetamide,N,N-dimethyl
  • Acetdimethylamide
  • acetic acid dimethylamide
  • Acetic acid-dimethylamide
  • DMA
  • N,N-Dimethylacetamid
  • N,N-dimethyl-acetamide
  • N,N-Dimethylethanamide
  • N-Acetyldimethylamine

MDL Number

MFCD00008686

Customs Code

2924199090

FAQ

What is N,N-Dimethylacetamide (CAS: 127-19-5)?

N,N-Dimethylacetamide (CAS: 127-19-5) is an organic compound commonly used in chemical synthesis. It has the chemical formula C4H9NO and is a colorless liquid with a faint amine odor. This compound is known for its solubility in water and organic solvents, as well as its ability to act as a solvent and intermediate. Its polarity and stability make it useful in various chemical processes, including pharmaceutical and industrial applications.

What are the main uses of N,N-Dimethylacetamide (CAS: 127-19-5)?

N,N-Dimethylacetamide (CAS: 127-19-5) is widely used in pharmaceuticals as a solvent and intermediate for drug synthesis. It also serves as a key component in polymer production and as a stabilizer in chemical reactions. In research, it is employed in organic chemistry for its ability to dissolve a variety of substances. Its applications span across industries, including coatings, adhesives, and chemical manufacturing, due to its versatile chemical properties.

Is N,N-Dimethylacetamide (CAS: 127-19-5) safe?

N,N-Dimethylacetamide (CAS: 127-19-5) is considered safe when handled properly, but it may cause mild irritation to the eyes, skin, and respiratory system. Safety standards recommend using appropriate protective equipment, such as gloves and goggles, and ensuring good ventilation. It is classified as a low hazard chemical, though long-term exposure should be avoided. Always follow safety guidelines for chemical handling and disposal.

How should N,N-Dimethylacetamide (CAS: 127-19-5) be stored?

N,N-Dimethylacetamide (CAS: 127-19-5) should be stored in a cool, dry, and well-ventilated area, away from direct sunlight. It is best kept in sealed, airtight containers to prevent evaporation and contamination. Maintain storage temperature below 25°C and humidity levels under 60% to ensure stability. Avoid exposure to incompatible materials and store in a fireproof cabinet if necessary.

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