Tigecycline (open C-ring D-ring) Quinone

Basic Information

View in Editor

CAS Number

1268494-46-7

Molecular Formula

C26H32N4O8

Molecular Weight

528.55 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

SMILES

View in Editor

CC(C)(C)NCC(=O)NC1=CC(=C2CC(CC(=O)C2=C1O)CC3=C(C(=O)C(=C(C3=O)O)C(=O)N)O)N(C)C

InChI

InChI=1S/C26H32N4O8/c1-26(2,3)28-10-17(32)29-14-9-15(30(4)5)12-6-11(8-16(31)18(12)22(14)35)7-13-20(33)23(36)19(25(27)38)24(37)21(13)34/h9,11,28,33,35,37H,6-8,10H2,1-5H3,(H2,27,38)(H,29,32)

InChIKey

YHJHYYJWUGHMDY-UHFFFAOYSA-N

LogP

1.1813000000000013

Topological Polar Surface Area

199.35999999999999 Å²

Hydrogen Bond Donor/Acceptor

7 / 12

Complexity

1100

Synonyms & References

English

Tigecycline (open C-ring D-ring) Quinone
(S)-4-((6-(2-(tert-Butylamino)acetamido)-8-(dimethylamino)-5-hydroxy-4-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)methyl)-2,5-dihydroxy-3,6-dioxocyclohexa-1,4-dienecarboxamide
4-[[(2S)-6-[[2-(Tert-butylamino)acetyl]amino]-8-(dimethylamino)-5-hydroxy-4-oxo-2,3-dihydro-1H-napht

FAQ

What is Tigecycline (CAS: 1268494-46-7)?

Tigecycline (CAS: 1268494-46-7) is a semi-synthetic derivative of tetracycline with broad-spectrum antibacterial activity, including activity against multi-drug resistant bacteria. It is characterized by its ability to inhibit bacterial protein synthesis by binding to the 30S ribosomal subunit.

What are the main uses of Tigecycline (CAS: 1268494-46-7)?

Tigecycline (CAS: 1268494-46-7) is primarily used in the treatment of serious infections such as skin and skin structure infections, intra-abdominal infections, complicated urinary tract infections, and pneumonia. It is also used in patients who are unable to receive other antibiotics due to allergies or resistance.

Is Tigecycline (CAS: 1268494-46-7) safe?

Tigecycline (CAS: 1268494-46-7) is generally considered safe when used under medical supervision. However, it may cause side effects such as nausea, vomiting, and photosensitivity. It is important to follow the prescribed dosage and avoid prolonged sun exposure while taking this medication.

How should Tigecycline (CAS: 1268494-46-7) be stored?

Tigecycline (CAS: 1268494-46-7) should be stored at a temperature below 25°C (77°F) and protected from light. The drug should be kept in a tight, light-resistant container to prevent degradation. Avoid storing it in areas with high humidity or direct sunlight, and keep it out of reach of children.