Erythromycin Ethylsuccinate

Basic Information

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CAS Number

1264-62-6

Molecular Formula

C43H75NO16

Molecular Weight

862.06 g/mol

Basic Physical Properties

Melting Point

219-224 C

Boiling Point

818.4°C at 760 mmHg

Water Solubility

Freely soluble in organic solvents, practically insoluble in water

Flash Point

>110°(230°F)

Solubility

ethanol: soluble50mg/mL

Refractive Index

1.5280 (estimate)

SMILES

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CC[C@H]1[C@]([C@H]([C@@H](C(=O)[C@H](C[C@]([C@H]([C@@H]([C@H]([C@@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)OC(=O)CCC(=O)OCC)(C)O)C)C)O)(C)O

InChI

InChI=1S/C43H75NO16/c1-15-29-43(11,52)36(48)24(5)33(47)22(3)20-41(9,51)38(25(6)34(26(7)39(50)57-29)59-32-21-42(10,53-14)37(49)27(8)56-32)60-40-35(28(44(12)13)19-23(4)55-40)58-31(46)18-17-30(45)54-16-2/h22-29,32,34-38,40,48-49,51-52H,15-21H2,1-14H3/t22-,23+,24+,25+,26-,27-,28-,29-,32-,34+,35+,36-,37-,38-,40-,41-,42+,43-/m0/s1

InChIKey

NSYZCCDSJNWWJL-XJHUJGFMSA-N

LogP

2.6798000000000077

Topological Polar Surface Area

226.27999999999997 Å²

Hydrogen Bond Donor/Acceptor

4 / 17

Complexity

1450

Safety Information

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GHS Hazard Pictograms

H317

H334

Hazard Statement

H317 May cause an allergic skin reaction
Sensitization, Skin

H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Sensitization, respiratory

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

ErythromycinEthylsuccinate
ERYTHROMYCIN 2'-(ETHYL BUTANEDIOATE)
ERYTHROMYCIN 2'-(ETHYL SUCCINATE)
erythrocinethylsuccinate
erythromycin,mono(ethylsuccinate)
erythromycin,mono(ethylsuccinate)(ester)
Succinic acid, monoester with erythromycin
Erythromycin 2''-[3-(ethoxycarbonyl)propionate]
EES
ERYTHROMYCIN ETHYISUCCINATE
ERYTHROMYCIN ETHYLSUCCINATE API
ERYTHROMYCIN ETHYLSUCCINATE, ANTIBIOTIC FOR CULTURE MEDIA USE ONLY
Erythromycinethyl succinate (6CI)
Erythromycin, 2'-(ethyl succinate) (7CI)
Erythromycin,mono(ethyl succinate) (ester) (8CI)
Oxacyclotetradecane, erythromycin deriv.
Succinic acid, ethyl ester, monoester with erythromycin (8CI)
Anamycin
Arpimycin
Durapaediat
E-Mycin e
Eritrocina
EryPed
Eryliquid
ErythroES
Erythro-Holz
Erythroped
Esinol
Evesin
Monomycin
Paediathrocin

MDL Number

MFCD00084692

Customs Code

2941500000

FAQ

What is Erythromycin Ethylsuccinate (CAS: 1264-62-6)?

Erythromycin Ethylsuccinate (CAS: 1264-62-6) is a semi-synthetic macrolide antibiotic derived from erythromycin. Its chemical formula is C37H67NO13, and it is typically a white crystalline powder with good solubility in water. This compound is used to treat bacterial infections by inhibiting protein synthesis in sensitive microorganisms.

What are the main uses of Erythromycin Ethylsuccinate (CAS: 1264-62-6)?

Erythromycin Ethylsuccinate (CAS: 1264-62-6) is primarily used as an oral antibiotic for respiratory tract infections, skin infections, and genital infections. It targets bacteria such as Streptococcus, Mycoplasma, and Chlamydia. Additionally, it is employed in veterinary medicine and research for antimicrobial applications.

Is Erythromycin Ethylsuccinate (CAS: 1264-62-6) safe?

Erythromycin Ethylsuccinate (CAS: 1264-62-6) is generally safe when used as directed by healthcare professionals. It is FDA-approved for therapeutic use, but like all medications, it may cause side effects such as gastrointestinal discomfort. Proper handling and adherence to safety guidelines are essential to minimize risks, especially during storage and disposal.

How should Erythromycin Ethylsuccinate (CAS: 1264-62-6) be stored?

Erythromycin Ethylsuccinate (CAS: 1264-62-6) should be stored in a cool, dry place at 15-25°C, away from moisture and light. It is best kept in airtight containers to maintain stability and prevent degradation. Avoid storing in bathrooms or areas with high humidity to preserve its efficacy and safety.