4-(4-Biphenylyl)-2-chloroquinazoline

Basic Information

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CAS Number

1262866-93-2

Molecular Formula

C20H13ClN2

Molecular Weight

316.78 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Solubility

Insuluble (2.1E-3 g/L) (25 ºC),

SMILES

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Clc1nc2ccccc2c(n1)c1ccc(cc1)c1ccccc1

InChI

InChI=1S/C20H13ClN2/c21-20-22-18-9-5-4-8-17(18)19(23-20)16-12-10-15(11-13-16)14-6-2-1-3-7-14/h1-13H

InChIKey

VSMPNDGQPFFGPG-UHFFFAOYSA-N

LogP

5.617200000000004

Topological Polar Surface Area

25.78 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Synonyms & References

English

Quinazoline, 4-[1,1'-biphenyl]-4-yl-2-chloro-
4-(biphenyl-4-yl)-2-chloroquinazoline
4-[1,1'-Biphenyl]-4-yl-2-chloroquinazoline
4-(4-Biphenylyl)-2-chloroquinazoline

MDL Number

MFCD28967157

FAQ

What is 4-(4-Biphenylyl)-2-chloroquinazoline (CAS: 1262866-93-2)?

4-(4-Biphenylyl)-2-chloroquinazoline is a chemical compound with the CAS number 1262866-93-2. It is a quinazoline derivative with a biphenyl group at position 4 and a chlorine atom at position 2. This compound is colorless to white crystals with a low melting point and a characteristic odor.

What are the main uses of 4-(4-Biphenylyl)-2-chloroquinazoline (CAS: 1262866-93-2)?

4-(4-Biphenylyl)-2-chloroquinazoline is primarily used in pharmaceutical research and development as a potential anticancer drug. It has shown promising activity against certain types of cancer cells. Additionally, it may have industrial applications in the synthesis of other chemical compounds.

Is 4-(4-Biphenylyl)-2-chloroquinazoline (CAS: 1262866-93-2) safe?

4-(4-Biphenylyl)-2-chloroquinazoline is generally safe when handled with proper precautions. However, exposure to the skin or inhalation of dust can cause irritation. It is important to use appropriate personal protective equipment (PPE) such as gloves and goggles. Avoid contact with eyes and skin, and keep the compound away from heat and sources of ignition.

How should 4-(4-Biphenylyl)-2-chloroquinazoline (CAS: 1262866-93-2) be stored?

4-(4-Biphenylyl)-2-chloroquinazoline should be stored in a cool, dry place away from direct sunlight and heat sources. Store it in a tightly sealed container to prevent moisture and light exposure. The storage temperature should not exceed 25°C (77°F). Keep it out of reach of children and ensure proper labeling.