3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(2-{3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy}ethyl)propanamide | CAS No. 1260092-50-9

3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(2-{3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy}ethyl)propanamide

Basic Information

CAS Number

1260092-50-9

Molecular Formula

C16H19N3O8

Molecular Weight

381.34 g/mol

AD

Basic Physical Properties

O=C(ON1C(CCC1=O)=O)CCOCCNC(CCN2C(C=CC2=O)=O)=O

InChI

InChI=1S/C16H19N3O8/c20-11(5-8-18-12(21)1-2-13(18)22)17-7-10-26-9-6-16(25)27-19-14(23)3-4-15(19)24/h1-2H,3-10H2,(H,17,20)

InChIKey

QXGYXAOYQWRQRZ-UHFFFAOYSA-N

LogP

-1.568399999999997

Topological Polar Surface Area

139.39 Ų

Hydrogen Bond Donor/Acceptor

1 / 11

Complexity

653

Synonyms & References

English

  • 2,5-dioxopyrrolidin-1-yl 3-(2-(3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido)ethoxy)propanoate
  • Mal-PEG-NHS
  • Mal-amido-PEG1-C2-NHS ester
  • Mal-amido-PEG1-C2-?NHS ester
  • (2,5-dioxopyrrolidin-1-yl) 3-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]propanoate

MDL Number

MFCD20229604

FAQ

What are the physical and chemical properties of 3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(2-{3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy}ethyl)propanamide (CAS: 1260092-50-9)?

3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(2-{3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy}ethyl)propanamide is a crystalline solid with a molecular weight of approximately 481.4 g/mol. It has low solubility in water but good solubility in common organic solvents like DMSO and DMF. The compound is reactive towards nucleophiles and can undergo hydrolysis under basic conditions. It is also prone to oxidation under certain conditions.

How is 3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(2-{3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy}ethyl)propanamide (CAS: 1260092-50-9) typically synthesized?

3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(2-{3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy}ethyl)propanamide is synthesized via a multi-step process involving the condensation of a pyrrolidinone derivative with an amine, followed by an acylation step. The synthesis typically involves the use of mild bases and catalysts to achieve high selectivity and yield. This compound is synthesized using standard laboratory techniques.

What industries use 3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(2-{3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy}ethyl)propanamide (CAS: 1260092-50-9)?

3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(2-{3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy}ethyl)propanamide finds application in the pharmaceutical industry, where it is used as a potential drug candidate. It may also be used in the synthesis of other complex organic compounds and in research and development for new materials and sensors.

What precautions should be taken when handling 3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(2-{3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy}ethyl)propanamide (CAS: 1260092-50-9)?

When handling 3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(2-{3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy}ethyl)propanamide, it is important to wear appropriate personal protective equipment (PPE), such as gloves, goggles, and a lab coat. Work should be performed in a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbent materials and the area should be rinsed with water. Consult the Material Safety Data Sheet (MSDS/SDS) for specific safety guidelines and emergency procedures.

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