Disodium (11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl phosphate | CAS No. 125-02-0

Disodium (11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl phosphate

Basic Information

CAS Number

125-02-0

Molecular Formula

C21H27Na2O8P

Molecular Weight

484.4 g/mol

AD

Basic Physical Properties

Boiling Point

674.8 oC at 760 mmHg

Flash Point

361.9 oC

Specific Rotation

D25 +102.5°

CC12CC(C3C(C1CCC2(C(=O)COP(=O)([O-])[O-])O)CCC4=CC(=O)C=CC34C)O.[Na+].[Na+]

InChI

InChI=1S/C21H29O8P.2Na/c1-19-7-5-13(22)9-12(19)3-4-14-15-6-8-21(25,17(24)11-29-30(26,27)28)20(15,2)10-16(23)18(14)19;;/h5,7,9,14-16,18,23,25H,3-4,6,8,10-11H2,1-2H3,(H2,26,27,28);;/q;2*+1/p-2/t14-,15-,16-,18+,19-,20-,21-;;/m0../s1

InChIKey

VJZLQIPZNBPASX-OJJGEMKLSA-L

LogP

2.55100

Complexity

878

Safety Information

View Safety Information

GHS Hazard Pictograms

H361H361

Hazard Statement

H361 Suspected of damaging fertility or the unborn child
Reproductive toxicity

Synonyms & References

English

  • Codelsol
  • AKOS025310687
  • sodium 2-((8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl phosphate
  • Phortisolone
  • EINECS 204-722-9
  • PREDNISOLONI NATRII PHOSPHAS [WHO-IP LATIN]
  • Key-Pred SP
  • NSC-759187
  • NEO-HYDELTRASOL COMPONENT PREDNISOLONE SODIUM PHOSPHATE
  • prednisolone phosphate, sodium salt, (11beta)-isomer
  • Q27280910
  • Prednisoloni natrii phosphas
  • Prednisolone sodium phosphate (USP:JAN)
  • Prednisolone Sodium Phosphate Oral Solution
  • 11.BETA.,17,21-TRIHYDROXYPREGNA-1,4-DIENE-3,20-DIONE 21-(DISODIUM PHOSPHATE
  • PREDNISOLONE SODIUM PHOSPHATE [ORANGE BOOK]
  • 11beta,17alpha-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl phosphate disodium
  • Prednis-A-Vet Injection
  • IV021NXA9J
  • PREDNISOLONE SODIUM PHOSPHATE (EP MONOGRAPH)
  • PREDNISOLONE SODIUM PHOSPHATE [WHO-DD]
  • PREDNISOLONE SODIUM PHOSPHATE (USP MONOGRAPH)
  • CHEMBL1201014
  • Predsol
  • CHEBI:8379
  • Prednisolone sodium phosphate (JP17/USP)
  • Prednesol
  • MFCD00083682
  • Prednisolone (disodium phosphate)
  • Pregna-1,4-diene-3,20-dione, 11-beta,17,21-trihydroxy-, 21-(dihydrogen phosphate), disodium salt
  • Prednisolone phosphate sodium

MDL Number

MFCD00083682

Customs Code

2937229000

FAQ

What is Disodium (11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl phosphate (CAS: 125-02-0)?

Disodium (11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl phosphate (CAS: 125-02-0) is a chemical compound commonly used in pharmaceutical research. It belongs to the class of steroid derivatives and functions as a phosphate ester. The compound has a molecular formula of C23H37O10PNa2 and is typically a white to off-white solid with a high melting point. It is known for its stability under normal conditions and solubility in polar solvents.

What are the main uses of Disodium (11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl phosphate (CAS: 125-02-0)?

Disodium (11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl phosphate (CAS: 125-02-0) is primarily used in pharmaceutical research as a precursor for the synthesis of corticosteroids. It is also employed in the development of drugs related to inflammation and immune response. Additionally, it serves as a key intermediate in the production of various steroid-based medications and has applications in biochemical studies and industrial processes involving steroid chemistry.

Is Disodium (11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl phosphate (CAS: 125-02-0) safe?

Disodium (11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl phosphate (CAS: 125-02-0) is generally considered safe when handled properly. However, it may cause irritation to the skin, eyes, or respiratory system upon exposure. Safety precautions include wearing appropriate personal protective equipment (PPE) and following standard laboratory safety protocols. It is not classified as highly toxic but should be treated with care during storage and use.

How should Disodium (11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl phosphate (CAS: 125-02-0) be stored?

Disodium (11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl phosphate (CAS: 125-02-0) should be stored in a cool, dry, and dark location to maintain its stability. It is best kept in a sealed container at a temperature below 25°C and away from moisture and direct light. Proper storage helps prevent degradation and ensures the compound remains effective for research or industrial applications.

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