Tolterodine tartrate

Basic Information

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CAS Number

124937-52-6

Molecular Formula

C26H37NO7

Molecular Weight

475.58 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Solid

Melting Point

205-210 ºC

Boiling Point

243.3°C at 760 mmHg

Flash Point

192.1℃

Specific Rotation

54625 +36.0°

SMILES

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CC1=CC(=C(C=C1)O)C(CCN(C(C)C)C(C)C)C2=CC=CC=C2.C(C(C(=O)O)O)(C(=O)O)O

InChI

InChI=1S/C22H31NO.C4H6O6/c1-16(2)23(17(3)4)14-13-20(19-9-7-6-8-10-19)21-15-18(5)11-12-22(21)24;5-1(3(7)8)2(6)4(9)10/h6-12,15-17,20,24H,13-14H2,1-5H3;1-2,5-6H,(H,7,8)(H,9,10)/t20-;1-,2-/m11/s1

InChIKey

TWHNMSJGYKMTRB-KXYUELECSA-N

LogP

3.2188200000000013

pKa

9.87(at 25℃)

Topological Polar Surface Area

138.53 Å²

Hydrogen Bond Donor/Acceptor

5 / 8

Complexity

474

Safety Information

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Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H361 Suspected of damaging fertility or the unborn child
Reproductive toxicity

H411 Toxic to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard

Toxicity

LD50 i.v. in male mice: 10-20 mg/kg (Jnsson)

Synonyms & References

English

4-methylphenol (2R,3R)-2,3-dihydroxysuccinate
CHEBI:32245
DTXSID80924972
2-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-methylphenol (2R,3R)-2,3-dihydroxybutanedioate
TOLTERODINE TARTRATE (EP MONOGRAPH)
SMR002544692
(2R,3R)-2,3-dihydroxybutanedioic acid;2-[(1R)-3-[di(propan-2-yl)amino]-1-phenylpropyl]-4-methylphenol
BT164484
Tolterodine Tartrate Extended Release
TOLTERODINE TARTRATE (USP-RS)
(2R,3R)-2,3-dihydroxybutanedioic acid; 2-[(1R)-3-[bis(propan-2-yl)amino]-1-phenylpropyl]-4-methylphenol
AKOS015961803
Q27114836
CCG-221263
PNU 200583E
A890340
tolterodine, tartrate
(R)-2-(3-(Bis(1-methylethyl)amino)-1-phenylpropyl)-4-methylphenol (R-(R*,R*))-2,3-dihydroxybutanedioate (1:1) (salt)
(+)-(r)-2-(a-[2-(diisopropylamino)ethyl]benzyl)-p-cresol tartrate
(+)-(R)-2-(I-(2-(Diisopropylamino)ethyl)benzyl)-p-cresol L-tartrate (1:1) (salt)
Z2235801945
(+)-r)-2-{a-(2-(diisopropylamino)ethyl)benzyl}-p-cresol tartrate
5T619TQR3R
Kabi-2234; PNU-200583E
Detrol LA;Kabi-2234;PNU-200583E
TOLTERODINE TARTRATE (MART.)
124937-52-6
Phenol, 2-((1R)-3-(bis(1-methylethyl)amino)-1-phenylpropyl)-4-methyl-, (2R,3R)-2,3-dihydroxybutanedioate (1:1) (salt)
s2550
SW197495-2
TOLTERODINE L-TARTRATE [WHO-DD]

MDL Number

MFCD07771985

Customs Code

2922299090

FAQ

What is Tolterodine tartrate (CAS: 124937-52-6)?

Tolterodine tartrate is a prescription medication used primarily to treat overactive bladder. It is a derivative of tolterodine, which is an anticholinergic drug. The chemical formula of Tolterodine tartrate is C16H22N2O4·C4H6O6. It is a white to off-white crystalline powder with good solubility in water and organic solvents, and is commonly used in pharmaceutical formulations for its efficacy in reducing urinary frequency and incontinence.

What are the main uses of Tolterodine tartrate (CAS: 124937-52-6)?

Tolterodine tartrate is mainly used in the treatment of overactive bladder symptoms, including urinary frequency, urgency, and incontinence. It is also used for managing symptoms of bladder spasms and other urinary disorders. As a pharmaceutical compound, it is commonly found in medications like Detrol LA, which is prescribed for patients with neurogenic bladder or other conditions affecting bladder control. Its use is primarily limited to medical applications due to its specific pharmacological activity.

Is Tolterodine tartrate (CAS: 124937-52-6) safe?

Tolterodine tartrate is generally considered safe when used as directed, but it may cause side effects such as dry mouth, constipation, and dizziness. It is important to handle the compound with care, especially in industrial or research settings, to avoid inhalation or skin contact. Safety standards for Tolterodine tartrate include following proper storage and handling protocols, and consulting healthcare professionals or safety guidelines for its use in pharmaceutical applications.

How should Tolterodine tartrate (CAS: 124937-52-6) be stored?

Tolterodine tartrate should be stored in a cool, dry place away from direct light. It is typically kept in a sealed container to maintain its stability and prevent moisture absorption. The recommended storage temperature is between 15°C to 30°C (59°F to 86°F), and it should be protected from humidity and light exposure to preserve its potency and quality. Always follow the manufacturer's guidelines for specific storage conditions.