Valaciclovir EP Impurity E (Valacyclovir USP Related Compound E)

Basic Information

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CAS Number

124832-31-1

Molecular Formula

C21H26N6O6

Molecular Weight

458.48 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Density

1.429

Refractive Index

1.644

SMILES

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CC(C)C(C(=O)OCCOCN1C=NC2=C1N=C(NC2=O)N)NC(=O)OCC3=CC=CC=C3

InChI

InChI=1S/C21H26N6O6/c1-13(2)15(24-21(30)33-10-14-6-4-3-5-7-14)19(29)32-9-8-31-12-27-11-23-16-17(27)25-20(22)26-18(16)28/h3-7,11,13,15H,8-10,12H2,1-2H3,(H,24,30)(H3,22,25,26,28)/t15-/m0/s1

InChIKey

ZQSUAJRZJTUOEA-HNNXBMFYSA-N

LogP

1.170100000000001

Topological Polar Surface Area

163.44999999999996 Å²

Hydrogen Bond Donor/Acceptor

4 / 12

Complexity

726

Synonyms & References

English

UNII-D5326179KU
Q27276106
2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl N-[(benzyloxy)carbonyl]-L-valinate
Acyclovir N-(phenylmethoxy)carbonyl-L-valinate
(S)-2-((2-Imino-6-oxo-2,3-dihydro-1H-purin-9(6H)-yl)methoxy)ethyl 2-(((benzyloxy)carbonyl)amino)-3-methylbutanoate
Cbz-?Valaciclovir
N-[(benzyloxy)carbonyl]-L-valine-2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl ester
VALACICLOVIR HYDROCHLORIDE IMPURITY E [EP IMPURITY]
HY-126375
Valaciclovir hydrochloride, anhydrous specified impurity E [EP]
SCHEMBL4910722
NS00007575
Benzyloxycarbonyl valacyclovir
Valaciclovir impurity E
DTXSID10924945
D5326179KU
ZQSUAJRZJTUOEA-HNNXBMFYSA-N
AKOS015896078
(S)-2-((2-Amino-6-oxo-1H-purin-9(6H)-yl)methoxy)ethyl 2-(((benzyloxy)carbonyl)amino)-3-methylbutanoate
N-[(Phenylmethoxy)carbonyl]-L-valine 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl ester
2-[(2-amino-6-oxo-3H-purin-9-yl)methoxy]ethyl (2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoate
2-[(2-amino-6-oxo-1H-purin-9-yl)methoxy]ethyl (2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoate
AC-23936
CS-0103190
(S)-2-((2-Amino-6-oxo-1H-purin-9(6H)-yl)methoxy)ethyl2-(((benzyloxy)carbonyl)amino)-3-methylbutanoate
A805304
124832-31-1
AKOS025401642
2-((2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)ethyl N-((benzyloxy)carbonyl)-L-valinate
Z-valacyclovir
Valacyclovir Related Compound E

MDL Number

MFCD08273968

FAQ

What is Valaciclovir EP Impurity E (CAS: 124832-31-1)?

Valaciclovir EP Impurity E, also known as Valacyclovir USP Related Compound E, is a chemical compound used in the manufacturing process of valacyclovir. It has a CAS number of 124832-31-1 and is a byproduct in the synthesis of antiviral drugs, particularly for treating herpes simplex and herpes zoster infections.

What are the main uses of Valaciclovir EP Impurity E (CAS: 124832-31-1)?

Valaciclovir EP Impurity E is primarily used in the pharmaceutical industry as a quality control impurity in the synthesis and testing of valacyclovir. It is not used in the final drug product but is important for ensuring the purity and consistency of the manufactured drug.

Is Valaciclovir EP Impurity E (CAS: 124832-31-1) safe?

Valaciclovir EP Impurity E, like other chemical compounds, should be handled with caution. It is safe when used under controlled laboratory conditions and in compliance with safety guidelines. Proper protective equipment and storage conditions are essential to minimize exposure and potential risks.

How should Valaciclovir EP Impurity E (CAS: 124832-31-1) be stored?

Valaciclovir EP Impurity E should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent contamination. The optimal storage conditions are temperatures below 25°C (77°F) and a relative humidity not exceeding 65%.