Z-Val-Val-Arg-AMC

Basic Information

View in Editor

CAS Number

124485-41-2

Molecular Formula

C34H45N7O7

Molecular Weight

663.8 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

View in Editor

CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CCCN=C(N)N)NC(=O)C(C(C)C)NC(=O)C(C(C)C)NC(=O)OCC3=CC=CC=C3

InChI

InChI=1S/C34H45N7O7/c1-19(2)28(40-32(45)29(20(3)4)41-34(46)47-18-22-10-7-6-8-11-22)31(44)39-25(12-9-15-37-33(35)36)30(43)38-23-13-14-24-21(5)16-27(42)48-26(24)17-23/h6-8,10-11,13-14,16-17,19-20,25,28-29H,9,12,15,18H2,1-5H3,(H,38,43)(H,39,44)(H,40,45)(H,41,46)(H4,35,36,37)/t25-,28-,29-/m0/s1

InChIKey

VCOVUYXJMHMVNV-FMYROPPKSA-N

LogP

2.6701200000000043

Topological Polar Surface Area

220.23999999999995 Å²

Hydrogen Bond Donor/Acceptor

8 / 14

Complexity

1190

Synonyms & References

English

SCHEMBL14050020
124485-41-2
Benzyl ((S)-1-(((S)-1-(((S)-5-guanidino-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate
Z-Val-Val-Arg-AMC
benzyl (S)-1-((S)-1-((S)-5-guanidino-1-(4-methyl-2-oxo-2H-chromen-7-ylamino)-1-oxopentan-2-ylamino)-3-methyl-1-oxobutan-2-ylamino)-3-methyl-1-oxobutan-2-ylcarbamate
Z-Val-Val-Arg-MCA
benzyl N-[(2S)-1-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate
BDBM210882
L-Argininamide,N-[(phenylmethoxy)carbonyl]-L-valyl-L-valyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
L-Argininamide,N-[(phenylmethoxy)carbonyl]-L-valyl-L-valyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7...
Z-VAL-VAL-ARG-AMC
Z-VAL-VAL-ARG-7-AMINO-4-METHYLCOUMARIN
Z-Val-Val-Arg-AMC · HCl
Z-VVR-AMC
C34H45N7O7
7979AH

MDL Number

MFCD00238523

FAQ

What regulatory guidelines apply to Z-Val-Val-Arg-AMC (CAS: 124485-41-2)?

Z-Val-Val-Arg-AMC (CAS: 124485-41-2) falls under the jurisdiction of the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) and may require specific handling and storage according to the REACH regulations in the European Union. For FDA and EPA requirements, specific testing and documentation may be necessary, especially if used in pharmaceutical or biotechnological applications.

Are there alternatives to Z-Val-Val-Arg-AMC (CAS: 124485-41-2) in synthesis?

There are several alternatives to Z-Val-Val-Arg-AMC (CAS: 124485-41-2) in synthesis, including other fluorogenic substrates like p-nitroanilide (pNA) or other amino acid-based substrates. These alternatives may offer different stability or reactivity profiles, making them suitable for various applications.

What is the market or research trend for Z-Val-Val-Arg-AMC (CAS: 124485-41-2)?

The market for Z-Val-Val-Arg-AMC (CAS: 124485-41-2) is driven by its extensive use in protease activity assays. Recent research trends include the development of more sensitive and specific fluorogenic substrates for various proteases, which may lead to increased demand and innovation in the field.

How should waste containing Z-Val-Val-Arg-AMC (CAS: 124485-41-2) be handled?

Waste containing Z-Val-Val-Arg-AMC (CAS: 124485-41-2) should be collected in appropriate containers and disposed of through professional waste disposal services. Incineration may be an option, but it should be conducted under controlled conditions to avoid environmental contamination. Proper environmental protection precautions, such as containment and neutralization of any residual chemicals, should be followed.