(11beta,16alpha)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione

Basic Information

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CAS Number

124-94-7

Molecular Formula

C21H27FO6

Molecular Weight

394.44 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Polymers and Plastics Thermoplastics Polyolefins

Basic Physical Properties

Melting Point

262-263 °C

Boiling Point

587.5°Cat760mmHg

Flash Point

309.1°C

Solubility

DMF: soluble20 mg/mL

Refractive Index

1.617

Specific Rotation

69 º (c=2, DMF)

SMILES

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CC12CC(C3(C(C1CC(C2(C(=O)CO)O)O)CCC4=CC(=O)C=CC43C)F)O

InChI

InChI=1S/C21H27FO6/c1-18-6-5-12(24)7-11(18)3-4-13-14-8-15(25)21(28,17(27)10-23)19(14,2)9-16(26)20(13,18)22/h5-7,13-16,23,25-26,28H,3-4,8-10H2,1-2H3/t13-,14-,15+,16-,18-,19-,20-,21-/m0/s1

InChIKey

GFNANZIMVAIWHM-OBYCQNJPSA-N

LogP

0.6204999999999998

Topological Polar Surface Area

115.06000000000002 Å²

Hydrogen Bond Donor/Acceptor

4 / 6

Complexity

807

Synonyms & References

English

9.alpha.-Fluoro-11.beta.,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
Ledercort
Kenacort-AG
EN300-7400440
D00385
CL 19823
BRN 2341955
(1R,2S,10S,11S,13R,14S,15S,17S)-1-fluoro-13,14,17-trihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one
9.alpha.-Fluoro-11.beta.,16.alpha.,17.alpha., 21-tetrahydroxypregna-1,4-diene-3,20-dione
EINECS 204-718-7
Prestwick3_000120
NCGC00021580-16
Volon
Triamcinolona (INN-Spanish)
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,16,17,21-tetrahydroxy-, (11-beta,16-alpha)-
Aristocort Tablets
Triamcet
TRIAMCINOLONE [HSDB]
9.alpha.-Fluoro-16.alpha.-hydroxyprednisolone
TRIAMCINOLONE [MART.]
SCHEMBL4447
MLS000028542
PREGNA-1,4-DIENE-3,20-DIONE, 9-FLUORO-11,16,17,21-TETRAHYDROXY-, (11.BETA.,16.ALPHA.)
Omcilon
Triamcinalone
Triamcinolone, United States Pharmacopeia (USP) Reference Standard
SDCCGSBI-0051146.P002
Triamcinolona [INN-Spanish]
HMS2095G22
11.beta.,16.alpha.,17.alpha., 21-Tetrahydroxy-9.alpha.-fluoro-1,4-pregnadiene-3,20-dione
9.alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahydroxypregna-1,4-diene-3,20-dione

MDL Number

MFCD00010477

Customs Code

2937229000

FAQ

What is (11beta,16alpha)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione (CAS: 124-94-7)?

This compound, with the CAS number 124-94-7, is a steroid derivative characterized by a fluoro group at position 9 and hydroxyl groups at positions 11, 16, 17, and 21. It belongs to the corticosteroid class and is known for its structural complexity, featuring double bonds at 1 and 4, and ketone groups at 3 and 20. Its molecular formula is C21H30FO6, and it exhibits typical steroid properties such as lipophilicity and potential biological activity.

What are the main uses of (11beta,16alpha)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione (CAS: 124-94-7)?

Primarily used as a pharmaceutical intermediate, this compound is involved in the synthesis of corticosteroids and related drugs. It also serves research purposes in studying steroid metabolism and bioactivity. Due to its chemical structure, it may find applications in organic synthesis and drug development, though specific industrial or food uses are not widely documented.

Is (11beta,16alpha)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione (CAS: 124-94-7) safe?

Safety depends on proper handling. While it is not classified as highly toxic, it may cause skin or eye irritation. Protective measures include wearing gloves, goggles, and a lab coat. Safety standards recommend adherence to OSHA guidelines for chemical exposure. Always follow established protocols for handling steroid compounds to ensure workplace safety.

How should (11beta,16alpha)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione (CAS: 124-94-7) be stored?

Store at 2-8°C in a cool, dry place, away from light. Keep in airtight containers to prevent moisture absorption. Maintain humidity levels below 60% to ensure stability. Avoid exposure to air and light to prevent degradation. Proper storage is critical to preserving the compound's integrity and efficacy.

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(11beta,16alpha)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione | CAS No. 124-94-7

Basic Information

CAS Number

Molecular Formula

Molecular Weight

Chemical Classification

Basic Physical Properties

Melting Point

Boiling Point

Flash Point

Solubility

Refractive Index

Specific Rotation

Chemical Properties

SMILES

InChI

InChIKey

LogP

Topological Polar Surface Area

Hydrogen Bond Donor/Acceptor

Complexity

Synonyms & References

English

MDL Number

Customs Code

FAQ

What is (11beta,16alpha)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione (CAS: 124-94-7)?

What are the main uses of (11beta,16alpha)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione (CAS: 124-94-7)?

Is (11beta,16alpha)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione (CAS: 124-94-7) safe?

How should (11beta,16alpha)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione (CAS: 124-94-7) be stored?

Related Compounds

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Supplier Information

Shandong Junrui Pharmaceutical Technology Co., Ltd.

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Hangzhou Yaorieyicheng Biopharmaceutical Co., Ltd.

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HePeng （ ShangHai ） Biotechnology Co Ltd

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