N~2~-[(Benzyloxy)carbonyl]-L-arginine

Basic Information

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CAS Number

1234-35-1

Molecular Formula

C14H20N4O4

Molecular Weight

308.34 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

171-174 °C (dec.) <br />171-174 °C (dec.)

Boiling Point

448.73°C (rough estimate)

Refractive Index

-10 ° (C=5.5, 0.2mol/L HCl)

Specific Rotation

-11 º (c=0.5, 0.5N HCl 24 ºC)

SMILES

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C1=CC=C(C=C1)COC(=O)NC(CCCN=C(N)N)C(=O)O

InChI

InChI=1S/C14H20N4O4/c15-13(16)17-8-4-7-11(12(19)20)18-14(21)22-9-10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H,18,21)(H,19,20)(H4,15,16,17)/t11-/m0/s1

InChIKey

SJSSFUMSAFMFNM-NSHDSACASA-N

LogP

0.62927

Topological Polar Surface Area

137.53 Å²

Hydrogen Bond Donor/Acceptor

6 / 8

Complexity

390

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

N-.alpha.-Cbz-L-arginine
2-{[(benzyloxy)carbonyl]amino}-5-carbamimidamidopentanoic acid
MLS000563719
Arginine, N2-[(phenylmethoxy)carbonyl]-
((Benzyloxy)carbonyl)-L-arginine
J-300035
R40
CMLD4_000213
A805075
N-.alpha.-(Benzyloxycarbonyl)arginine, L-
M03028
Nalpha-Carbobenzyloxy-L-arginine
(2S)-5-(diaminomethylideneamino)-2-(phenylmethoxycarbonylamino)pentanoic acid
N2-Benzyloxycarbonyl-L-arginine
SDCCGMLS-0091585.P001
NS00044181
Arginine, N2-carboxy-, N2-benzyl ester, L-
Benzyloxycarbonylarginine
SMR000388882
Nalpha-Carbobenzoxy-L-arginine
(2S)-5-[bis(azanyl)methylideneamino]-2-(phenylmethoxycarbonylamino)pentanoic acid
EINECS 214-973-6
(S)-N2-(benzyloxycarbonyl)-arginine
SCHEMBL631840
BDBM94463
HY-W011359
L-Arginine, N2-((phenylmethoxy)carbonyl)-
(2S)-5-(diaminomethylideneammonio)-2-(phenylmethoxycarbonylamino)pentanoate
CS-W012075
N~2~-[(benzyloxy)carbonyl]-L-arginine
N2-((Phenylmethoxy)carbonyl)-L-arginine

MDL Number

MFCD00001762

Customs Code

2925290090

FAQ

What regulatory guidelines apply to N~2~-[(Benzyloxy)carbonyl]-L-arginine (CAS: 1234-35-1)?

N~2~-[(Benzyloxy)carbonyl]-L-arginine (CAS: 1234-35-1) falls under the scope of the REACH regulation in the European Union, which requires comprehensive safety data sheets (SDS) and registration for substances above 1 ton per year. In the USA, it is regulated under the Toxic Substances Control Act (TSCA) by the EPA. Additionally, it is classified under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) for health and environmental hazards.

Are there alternatives to N~2~-[(Benzyloxy)carbonyl]-L-arginine (CAS: 1234-35-1) in synthesis?

Alternative reagents for N~2~-[(Benzyloxy)carbonyl]-L-arginine (CAS: 1234-35-1) include dipeptide building blocks such as N~2~-[(2-chloro-2-methylpropyloxy)carbonyl]-L-arginine or N~2~-[(tert-butoxycarbonyl)-L-arginine. These alternatives can be used in similar chemical reactions, providing flexibility in synthetic routes.

What is the market or research trend for N~2~-[(Benzyloxy)carbonyl]-L-arginine (CAS: 1234-35-1)?

The market for N~2~-[(Benzyloxy)carbonyl]-L-arginine (CAS: 1234-35-1) is growing due to its applications in pharmaceuticals and as a precursor in peptide synthesis. Research is focusing on its use in drug discovery and development, particularly in the treatment of cardiovascular diseases and inflammation. Market trends indicate increasing demand for this compound as its therapeutic potential is explored further.

How should waste containing N~2~-[(Benzyloxy)carbonyl]-L-arginine (CAS: 1234-35-1) be handled?

Waste containing N~2~-[(Benzyloxy)carbonyl]-L-arginine (CAS: 1234-35-1) should be collected in appropriate containers and stored in a well-ventilated area. It should be disposed of through professional waste disposal services that follow the regulations set by the EPA and OSHA. Environmental protection measures include proper containment to prevent leakage and precautionary measures to avoid skin and eye contact during handling.