Abemaciclib Impurity 19

Basic Information

View in Editor

CAS Number

1231930-25-8

Molecular Formula

C12H18BrN3

Molecular Weight

284.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

View in Editor

CCN1CCN(Cc2ccc(Br)nc2)CC1

InChI

InChI=1S/C12H18BrN3/c1-2-15-5-7-16(8-6-15)10-11-3-4-12(13)14-9-11/h3-4,9H,2,5-8,10H2,1H3

InChIKey

DMNPLEDMMNWHTL-UHFFFAOYSA-N

LogP

1.9816

Topological Polar Surface Area

19.37 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

204

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

1-[(6-bromo-3-pyridinyl)methyl]-4-ethylPiperazine
1-((6-Bromopyridin-3-yl)methyl)-4-ethylpiperazine
1-(6-bromo-pyridin-3-ylmethyl)-4-ethyl-piperazine
1-[(6-Bromo-3-pyridyl)methyl]-4-ethylpiperazine
1-[(6-bromopyridin-3-yl)methyl]-4-ethylpiperazine
Piperazine, 1-[(6-broMo-3-pyridinyl)Methyl]-4-ethyl-
DMNPLEDMMNWHTL-UHFFFAOYSA-N
BCP18172
AK341472
SY128068
J3.496.408D
Pipera

MDL Number

MFCD25977325

FAQ

What regulatory guidelines apply to Abemaciclib Impurity 19 (CAS: 1231930-25-8)?

Regulatory guidelines for Abemaciclib Impurity 19 (CAS: 1231930-25-8) include OSHA standards, GHS classification, REACH regulations, and FDA/EPA requirements. It is classified as a hazardous substance, and companies must comply with handling, storage, and disposal regulations to ensure safety and environmental protection.

Are there alternatives to Abemaciclib Impurity 19 (CAS: 1231930-25-8) in synthesis?

There are no direct alternatives to Abemaciclib Impurity 19 (CAS: 1231930-25-8); however, chemists can explore using different reagents or catalysts to synthesize Abemaciclib itself, which may reduce the generation of this impurity. It is essential to evaluate the feasibility and side effects of alternative methods.

What is the market or research trend for Abemaciclib Impurity 19 (CAS: 1231930-25-8)?

The research trend for Abemaciclib Impurity 19 (CAS: 1231930-25-8) is focused on developing more efficient and environmentally friendly purification techniques to minimize its presence in the final drug product. Market demand is driven by the increasing need for high-purity pharmaceuticals, particularly in oncology treatments.

How should waste containing Abemaciclib Impurity 19 (CAS: 1231930-25-8) be handled?

Waste containing Abemaciclib Impurity 19 (CAS: 1231930-25-8) should be collected in appropriate containers and disposed of through professional waste disposal services. Proper incineration or chemical treatment methods should be employed to ensure the safe and environmentally friendly removal of the impurity. Compliance with local and national regulations is crucial.