N-Methylformamide

Basic Information

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CAS Number

123-39-7

Molecular Formula

C2H5NO

Molecular Weight

59.07 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

−4 °C

Boiling Point

198-199 °C

Water Solubility

miscible

Refractive Index

n20/D 1.432(lit.)

SMILES

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CNC=O

InChI

InChI=1S/C2H5NO/c1-3-2-4/h2H,1H3,(H,3,4)

InChIKey

ATHHXGZTWNVVOU-UHFFFAOYSA-N

LogP

-0.6378000000000001

Topological Polar Surface Area

29.1 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

Safety Information

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GHS Hazard Pictograms

H312

H360

Hazard Statement

H312 Harmful in contact with skin
Acute toxicity, dermal

H360 May damage fertility or the unborn child
Reproductive toxicity

Toxicity

LD50 in mice (mg/kg): 2300 i.p.; 2600 orally; 1580 i.v.; 2700 i.m. (Langdon)

Synonyms & References

English

DTXSID0025608
NSC 3051
Formamide, N-methyl- ( )
n-methylcarboxamide
SB85388
863653-47-8
methanimidic acid, methyl-
N-Methyl-formimidic acid
N-METHYLFORMAMIDE
n-methyl-Formamide
Methylformamide
A805066
N-METHYLFORMAMIDE [HSDB]
N-Methylformamide, 99%
WLN: VHM1
X 188
FT-0652807
Formamide, N-methyl-
J-004934
EK 7011
EC 204-624-6
Z104473766
N-METHYL-FORMIC ACID-AMIDE
FT-0638572
AKOS000118787
N-Formylmethylamine
(Z)-methylimidoformic acid
HCONHCH3
n-methyl Formic acid amide
CHEBI:7438
CHEMBL9240

MDL Number

MFCD00003280

Customs Code

2924199090

FAQ

What is N-Methylformamide (CAS: 123-39-7)?

N-Methylformamide (CAS: 123-39-7) is a colorless, volatile liquid with the chemical formula C2H5NO. It exhibits polar aprotic solvent properties, is soluble in water and organic solvents, and has a boiling point of approximately 116°C. Commonly used in chemical synthesis, it serves as an intermediate in pharmaceutical and industrial applications.

What are the main uses of N-Methylformamide (CAS: 123-39-7)?

N-Methylformamide (CAS: 123-39-7) is widely used in pharmaceuticals as a solvent and intermediate in drug synthesis. Industrially, it functions as a raw material for producing dyes, textiles, and polymers. In research, it acts as a reagent for organic reactions. It is also applied in food industry processes as a flavoring agent and in analytical chemistry for sample preparation.

Is N-Methylformamide (CAS: 123-39-7) safe?

N-Methylformamide (CAS: 123-39-7) is not classified as carcinogenic but is considered hazardous due to its potential to cause eye and skin irritation. It has a flammable flash point, so handling requires protective equipment like gloves and goggles, proper ventilation, and adherence to OSHA and EPA safety guidelines. Avoid inhalation and contact with skin to ensure safe usage.

How should N-Methylformamide (CAS: 123-39-7) be stored?

Store N-Methylformamide (CAS: 123-39-7) in a cool, dry, and well-ventilated area, away from direct light and heat sources. Keep in sealed, airtight containers to prevent evaporation. Maintain temperatures below 25°C and avoid exposure to moisture or air to ensure stability. Always store in a fire-safe location due to its flammability.