2-Chloro-5-iodo-4-methoxypyridine

Basic Information

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CAS Number

1226878-98-3

Molecular Formula

C6H5ClINO

Molecular Weight

269.47 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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COc1cc(Cl)ncc1I

InChI

InChI=1S/C6H5ClINO/c1-10-5-2-6(7)9-3-4(5)8/h2-3H,1H3

InChIKey

LZAXKFPJNZLAJJ-UHFFFAOYSA-N

LogP

2.3482000000000003

Topological Polar Surface Area

22.12 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

114

Synonyms & References

English

2-chloro-5-iodo-4-methoxypyridine
LZAXKFPJNZLAJJ-UHFFFAOYSA-N
FCH1374147
Pyridine, 2-chloro-5-iodo-4-methoxy-
AK370017
AX8276458

MDL Number

MFCD18415711

FAQ

What are the physical and chemical properties of 2-Chloro-5-iodo-4-methoxypyridine (CAS: 1226878-98-3)?

2-Chloro-5-iodo-4-methoxypyridine has a crystalline form and a molecular weight of approximately 335.13 g/mol. It is slightly soluble in water but soluble in common organic solvents like ethanol and acetone. The compound shows moderate reactivity, particularly towards nucleophiles due to the presence of the iodo and methoxy groups.

How is 2-Chloro-5-iodo-4-methoxypyridine (CAS: 1226878-98-3) typically synthesized?

2-Chloro-5-iodo-4-methoxypyridine is typically synthesized through a multi-step process involving the introduction of chlorine, iodine, and methoxy groups onto a pyridine ring. Common methods include halogenation reactions and methylation under controlled conditions. The reaction yields are generally high, and the selectivity is good.

What industries use 2-Chloro-5-iodo-4-methoxypyridine (CAS: 1226878-98-3)?

2-Chloro-5-iodo-4-methoxypyridine is used in various industries, including pharmaceuticals for drug synthesis, and as a precursor in the development of new materials for sensors and semiconductors. Its unique chemical properties make it valuable in these applications.

What precautions should be taken when handling 2-Chloro-5-iodo-4-methoxypyridine (CAS: 1226878-98-3)?

When handling 2-Chloro-5-iodo-4-methoxypyridine, it is important to use personal protective equipment (PPE) including gloves and goggles. Work should be conducted in a well-ventilated area or fume hood. Spills should be handled carefully and cleaned up using appropriate absorbent materials. Refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.