5-[4,6-Di(4-morpholinyl)-1,3,5-triazin-2-yl]-4-(trifluoromethyl)-2(1H)-pyridinimine | CAS No. 1225037-39-7
5-[4,6-Di(4-morpholinyl)-1,3,5-triazin-2-yl]-4-(trifluoromethyl)-2(1H)-pyridinimine
Basic Information
CAS Number
1225037-39-7
Molecular Formula
C17H20F3N7O2
Molecular Weight
411.39 g/mol
AD
Chemical Classification
Basic Physical Properties
Boiling Point
643.7±65.0°C at 760 mmHg
Safety Information
View Safety InformationHazard Statement
H302
Harmful if swallowed
Acute toxicity, oral
Acute toxicity, oral
H315
Causes skin irritation
Skin corrosion/irritation
Skin corrosion/irritation
H319
Causes serious eye irritation
Serious eye damage/eye irritation
Serious eye damage/eye irritation
H335
May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Synonyms & References
English
- PI3K-IN-2
- 5-(4,6-dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine
- Bimiralisib
- PQR 309
- PQR-309
- PQR309
- 6Z3QHB00LB
- 5-[bis(morpholin-4-yl)-1,3,5-triazin-2-yl]-4-(trifluoromethyl)pyridin-2-amine
- 5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine
- pqr309-bimiralisib
- Bimiralisib [INN]
- Bimiralisib [USAN]
- PQR309; Bimiralisib
- Bimiralisib [WHO-DD]
- NCB5
- Bimiralisib (PQR309)
- Bimiralisib (USAN/INN)
- GTPL8383
- PQR309; Bimiralisib f
MDL Number
MFCD28902193
FAQ
What are the physical and chemical properties of 5-[4,6-Di(4-morpholinyl)-1,3,5-triazin-2-yl]-4-(trifluoromethyl)-2(1H)-pyridinimine (CAS: 1225037-39-7)?
5-[4,6-Di(4-morpholinyl)-1,3,5-triazin-2-yl]-4-(trifluoromethyl)-2(1H)-pyridinimine is a crystalline compound with a molecular weight of approximately 547.48 g/mol. It has low water solubility and good solubility in organic solvents like DMSO and DMF. It exhibits high thermal stability and moderate reactivity in certain chemical transformations.
How is 5-[4,6-Di(4-morpholinyl)-1,3,5-triazin-2-yl]-4-(trifluoromethyl)-2(1H)-pyridinimine (CAS: 1225037-39-7) typically synthesized?
This compound is typically synthesized through a multi-step process involving the reaction of 4,6-bis(4-morpholinyl)-1,3,5-triazine with 4-(trifluoromethyl)-2(1H)-pyridinimine under basic conditions. The synthesis involves the use of catalysts like sodium hydride and requires careful control of reaction temperature and time for high yield and selectivity.
What industries use 5-[4,6-Di(4-morpholinyl)-1,3,5-triazin-2-yl]-4-(trifluoromethyl)-2(1H)-pyridinimine (CAS: 1225037-39-7)?
5-[4,6-Di(4-morpholinyl)-1,3,5-triazin-2-yl]-4-(trifluoromethyl)-2(1H)-pyridinimine is used in various industries, particularly in pharmaceuticals for its potential in drug discovery and development. It also finds applications in the synthesis of organic semiconductors and as a precursor in the production of advanced polymers and sensors.
What precautions should be taken when handling 5-[4,6-Di(4-morpholinyl)-1,3,5-triazin-2-yl]-4-(trifluoromethyl)-2(1H)-pyridinimine (CAS: 1225037-39-7)?
When handling 5-[4,6-Di(4-morpholinyl)-1,3,5-triazin-2-yl]-4-(trifluoromethyl)-2(1H)-pyridinimine, it is essential to use proper personal protective equipment (PPE) such as gloves, goggles, and lab coats. Work should be conducted in a well-ventilated fume hood to minimize exposure. Spills should be cleaned up with care, and the material safety data sheet (MSDS) or SDS should be consulted for detailed spill cleanup procedures and emergency response guidelines.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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