Rupatadine Impurity C

Basic Information

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CAS Number

1224515-72-3

Molecular Formula

C45H43Cl2N5

Molecular Weight

724.78 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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C1CC2=C(C=CC(=C2)Cl)C(=C3CCN(CC3)CC4=CC(=CN=C4)CN5CCC(=C6C7=C(CCC8=C6N=CC=C8)C=C(C=C7)Cl)CC5)C9=C1C=CC=N9

InChI

InChI=1S/C45H43Cl2N5/c46-38-9-11-40-36(24-38)7-5-34-3-1-17-49-44(34)42(40)32-13-19-51(20-14-32)28-30-23-31(27-48-26-30)29-52-21-15-33(16-22-52)43-41-12-10-39(47)25-37(41)8-6-35-4-2-18-50-45(35)43/h1-4,9-12,17-18,23-27H,5-8,13-16,19-22,28-29H2

InChIKey

QMAUPLJMOVSLAU-UHFFFAOYSA-N

LogP

9.571399999999999

Topological Polar Surface Area

45.150000000000006 Å²

Hydrogen Bond Donor/Acceptor

0 / 5

Complexity

1170

Synonyms & References

English

5’-[(Desloratadine)methyl] Rupatadine
5'-[(Desloratadine)Methyl] Rupatadine
8-chloro-11-[1-[[5-[[4-(8-chloro-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-11-ylidene)piperidin-1-yl]methyl]pyridin-3-yl]methyl]piperidin-4-ylidene]-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridine
11,11'-[3,5-Pyridinediylbis(methylene-1,4-piperidinediyl)]bis[8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
5'-[(Desloratidine)methyl] Rupatadine
Rupatadine Impurity C
3,5-bis((4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidin-1-yl)methyl)pyridine
Rupatadine fumarate impurity C [EP]
13-chloro-2-[1-[[5-[[4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]methyl]pyridin-3-yl]methyl]piperidin-4-ylidene]-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene
5'-[(Desloratadine)methyl] Rupatadine
RUPATADINE FUMARATE IMPURITY C [EP IMPURITY]
11,11'-(3,5-Pyridinediylbis(methylene-1,4-piperidinediyl))bis(8-chloro-6,11-dihydro-5H-benzo(5,6)cyclohepta(1,2-b)pyridine)
XVV2J8NLL9
5H-Benzo(5,6)cyclohepta(1,2-b)pyridine, 11,11'-(3,5-pyridinediylbis(methylene-1,4-piperidinediyl))bis(8-chloro-6,11-dihydro-
SCHEMBL16385871
DTXSID60747540
11,11'-[Pyridine-3,5-diylbis(methylenepiperidin-1-yl-4-ylidene)]bis(8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine)
UNII-XVV2J8NLL9
1224515-72-3

MDL Number

MFCD28009430

FAQ

What regulatory guidelines apply to Rupatadine Impurity C (CAS: 1224515-72-3)?

Rupatadine Impurity C (CAS: 1224515-72-3) should comply with the Globally Harmonized System of Classification and Labeling of Chemicals (GHS), REACH regulations in the EU, and FDA/EPA requirements for chemical safety and environmental impact. Specific testing and documentation may be required for import, storage, and disposal to ensure compliance with local and international regulations.

Are there alternatives to Rupatadine Impurity C (CAS: 1224515-72-3) in synthesis?

For synthesis, alternatives to Rupatadine Impurity C (CAS: 1224515-72-3) may include isomers or analogs of rupatadine, such as other antihistamines or similar compounds. Common alternative reagents might be used to avoid this impurity, depending on the specific synthetic route and desired product purity.

What is the market or research trend for Rupatadine Impurity C (CAS: 1224515-72-3)?

The market for Rupatadine Impurity C (CAS: 1224515-72-3) is driven by ongoing research and development in antihistamine medications. Trends include a focus on reducing impurities to enhance drug efficacy and safety, with an increase in demand for analytical methods to detect and quantify this impurity. The trend also includes regulatory pressure to ensure drug purity, impacting the overall market dynamics.

How should waste containing Rupatadine Impurity C (CAS: 1224515-72-3) be handled?

Waste containing Rupatadine Impurity C (CAS: 1224515-72-3) should be collected and stored in appropriate containers, labeled with the correct hazard information. Proper incineration or professional waste disposal methods should be employed to ensure environmental safety. Ensure all handling and disposal procedures comply with local, state, and federal regulations to prevent environmental contamination and protect public health.